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Secondly, the merits of the ACR scoring system are complicated, as you suggest, and not necessarily perfectly suited to the ME situation. The multiple threshold structure means that scores of different measures are combined in a way that reflects our normal (and rational) algorithmic decision...

Firstly, let me post this comment from elsewhere to give a bit more background: A similar system for ME would be easy enough. We have discussed it in detail in years gone by. You need one or more subjective endpoints that are the most direct practical indicators of ill health - fatigue is the...

I am not sure about that. When we used penicillamine for rheumatoid a lot of patients lost their sense of smell and taste but they did not get malnourished. They just complained food was very dull.

I wasn't aware that Greenhalgh had anything to do with Independent SAGE? From the outset they were far more sensible than SAGE and their advice would have prevented the whole pandemic at least in Western countries. They may not be that good on LC but I had not heard of any comment on that.

So what on earth are they going to do with the fact that I said I was unhappy or depressed several days this week - which I was, because of having Covid, coming back from holiday and reading the news. It reminds me of those automatic telephone conversations when it says 'I didn't quite catch...

I emphasised that it is unethical to set up any integrated care pathway until they have some EVIDENCE that it is beneficial.

Moved post Oh dear me, I answered that very honestly indeed and told them what a lot of bullshit it was. Quite enjoyed it. Presumably NIHR funded. I am wondering who this Lyth Hishmeh guy is - I guess a psychologist?

Biobank cohorts are probably quite useful for genetic studies but for this sort of environmental factor study one would need to know that there were no various confounding associations. The lower rates of RA reported in Wales and Scotland versus England is odd for a start. The association with...

I wouldn't get too worried about what they say. It bears no relation to immunology as I know it. If you are physically active the T cells going and out of the blood are likely to be a bit busier just cleaning up mess. Mitochondrial mass is probably a measure of activation. It is quite normal for...

The best place to counter White's article may be in the next HealthSense Newsletter. I am surprised they published this but they have a 'right of reply' policy. We may be able to do something but this is such old ground it is hard to know what more to say. Carson has been asked to explain his...

I was well enough to go to Sainsbury's today so I expect to survive. (For those not in the UK the cryptic reference to Sainsbury's is an increasingly downmarket supermarket store that when I was a lad had sawdust on the floor and separate counters for eggs and bacon when we still had ration...

It's alright, I often do and the moderators are very good at erasing things.

Actually, faulty ideology did try to distort NICE's procedures by means of a text message or email to Gill Leng, but it didn't work out. Caroline and I (also with Covid again) have raised our eyebrows in the HealthSense chat room.

Actually, faulty ideology did try to distort NICE's procedures by means of a text message or email to Gill Leng, but it didn't work out. Caroline and I (also with Covid again) have raised our eyebrows in the HealthSense chat room.