Search results

That makes sense but the author of the review seemed to be advocating more than that.

I disagree. An association is evidence that there might be causation and for adverse events that is enough to advise against anything that might feed in to that. It is exactly the same as for GET in ME. I have written to say that I think the evidence for GET being harmful is sufficient to...

Yes, but from the way it is written that looks like a researcher touting for business rather than a balanced review. Anyone can write a review and say that.

I have looked through that blog piece @Arnie Pye and I really don't find any of those statistical quibbles very relevant. The main grouse seems to be against the hype a press release or cover article. One gets used to that.The fact remains that an association with bad outcome is a red flag...

I realise you think that but what reasons? Not sure which paper in link 3 you are referring to. The paper by Andres looks to me to be pushing a line, with a number of inconsistencies. I doubt a high B12 level is a useful route to diagnosis of any particular disease.

The authors of the original paper seem to be quite open about that and, as I indicated, it if you are worried about harm the question is whether there might be a causal relation But as far as I am aware this is a pretty rare situation. I never came across it in my practice. The paper looks at...

This seems to be just a speculation, without much going for it as far as I can see.

This looks pretty dubious. Is it wise for the Mortem group to be tweeting and effectively providing advertising? Research groups do not normally do that sort of thing.

I have only read the abstract of the paper but it seems perfectly fair to me. There is an association between high B12 levels and death. That proves no causal relation, as they say, but it raises a distinct possibility that having a high B12 level is bad for you. It is then very logical to...

I think it is very unlikely. Brain blood vessels are different from most others in being almost non-elastic tubes that ensure a constant volume of flow all the time. Raising blood pressure may increase flow but of course it also increases the risk of brain blood vessel rupture as stroke so it is...

In general exercise is likely to divert blood away from the brain to the muscles and skin. I suspect in fact the brain makes sure things do not change much for it. I suspect a sense of blood being pushed to the head is due to blood being pumped into the skin of the face, not the brain. Exercise...

What seems a bit confusing about that graph is that it only includes some rather uncommon causes of death. Stroke and pneumonia would be way off the scale. The total number of deaths in the world since January must be something like 50 million.

I had previously predicted that the UK would probably get its act together around July after various other countries had made mistakes and shown how important adequate restriction and test and trace was. I think I may have been a couple of weeks ahead of reality. It looks from the news today as...

What seems odd to me about this group is their openly discussing doing it, apparently unaware that human beings who are not psychologists might been earshot. In my experience mutual appreciation and troublemaker dumping amongst other communities is done rather more discreetly. Have suspicion...

Indeed. It seems that the primary aim of this type of clinical psychologist is to ingratiate oneself with ones peer group (even if that means including James Coyne) and to patronise patients. To advocate for patients in a way that is critical of peers is beyond the pale (as I was told by Michael...

Short abstract: A few patients were kind enough to humour us in our delusions. God knows why.

I would say the reverse. It is high time we went back to the concept of 'Natural Philosophy' as the study of the world at all levels, whether physical, biological or metaphysical. The divide between science and philosophy is entirely counterproductive!

Yes, I have a sense of another Cochrane situation here. Those who would be thought police are very likely to have an axe to grind of their own. We hear: Yet another initiative of MetaMelb is the development of concrete guidelines that peer reviewers could use to more uniformly assess research...

And this is on top of the £10billion not being provided in order for the NHS to even cope with the basic aftermath of the epidemic. Why don't they eat cake?

You could do a dose response study with 200, 600 and 1000ml. Even 200ml would lead to going for a pee. I would worry about the ethics of doing a larger study because central intravenous lines are not without serious morbidity.