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  1. Jonathan Edwards

    Coronavirus - worldwide spread and control

    It didn't even need to be as ruthless as that. The first wave of Chinese origin in the UK petered out on its own with some local tracing. By the second week of February it was clear that air traffic should stop and I think if it had then most countries could have taken the New Zealand path...
  2. Jonathan Edwards

    ME/CFS services in the United Kingdom

    I think that might be a bit like trying to abolish beer from inside a pub.
  3. Jonathan Edwards

    ME/CFS services in the United Kingdom

    It doesn't sound as if there is a lot of point in bothering: The postholder(s) will be an integral part of a dynamic, committed and compassionate multi-disciplinary team which is therapy-led.
  4. Jonathan Edwards

    (Thesis) Autoimmune aspects in ME/CFS: A literature study on indications of autoimmunity in ME/CFS [Swedish), 2020, Strahle

    I think this may refer to Jonas Blomberg's interest in HSP. HSP60 antibodies are everywhere and normal. The titres may be a bit higher in some autoimmune diseases but so are antibodies to all sorts of things. They do not indicate infection triggered disease as far as we know. Maybe the best...
  5. Jonathan Edwards

    Lightning Process study in Norway - Given Ethics Approval February 2022

    As I read it @strategist is questioning the statement that harassment is never OK. If the Act Up movement was harassment that is. I would also tend to question the idea that this is about harassment being OK since I see no harassment. Pointing out that studies are sufficiently flawed to be...
  6. Jonathan Edwards

    Who is Simon Wessely?

    I love the idea of Andy needing to be careful about posting on S4ME. Seriously, @Andy, now that you are an academic gearing up to publish major papers on ME, you may have to think about being 'loyal' to your colleagues as Michael Sharpe told me off for not being. You may no longer be able to be...
  7. Jonathan Edwards

    Coronavirus - worldwide spread and control

    I don't think we should be depressed by what Tedros is saying. The pandemic is bound to be speeding up at this stage because it is still getting in to new areas. He is simply pointing out that it is crazy for countries to start easing off restrictions when we are still maybe only 10% into the...
  8. Jonathan Edwards

    The biology of coronavirus COVID-19 - including research and treatments

    I wouldn't personally put any weight on this finding.T cell responses are notoriously difficult to interpret. Antibody responses are 100 times more reliable across the board. Antibody tests are the gold standard. There seem to be a proportion of scientists motivated to show that things are not...
  9. Jonathan Edwards

    Graded exercise therapy doesn’t restore the ability to work in ME/CFS. Rethinking of a Cochrane review, 2020, Vink & Vink-Niese

    I think poor Dr Winarick is a bit challenged on the valid construct front himself: ABOUT DR. DANIEL WINARICK As a licensed clinical psychologist in Manhattan, my central priority is to bring happiness and well-being to your life by restoring your mental balance. I want to help you break free...
  10. Jonathan Edwards

    UK: Priority Setting Partnership: Medically Not Yet Explained Symptoms - 10 top priorities published July 2022

    A: What do you do with nuisance patients boss? B: Empathise with them until they are fed up to the back teeth with being empathised with and go away. And put the few that like the empathy on your patient advisory group. A: So how do you show empathy? B: You say how much you empathise with their...
  11. Jonathan Edwards

    Graded exercise therapy doesn’t restore the ability to work in ME/CFS. Rethinking of a Cochrane review, 2020, Vink & Vink-Niese

    Maybe rather than commissioning another review using its not fit for purpose tools Cochrane should simply decide whether it accepts the verdict of this one - and if not why not. The due diligence has been done. All that is required is assessment of the conclusions. But maybe Cochrane is more...
  12. Jonathan Edwards

    UK: Priority Setting Partnership: Medically Not Yet Explained Symptoms - 10 top priorities published July 2022

    I looked up who James Lind Alliance are. It seems they were set up by Iain Chalmers of Cochrane, together with John Scadding who was dean of Royal Society of Medicine at the time and is probably not a key player. Subsequently the JLI became a sort of quango within NIHR it seems. My guess is that...
  13. Jonathan Edwards

    UK: Priority Setting Partnership: Medically Not Yet Explained Symptoms - 10 top priorities published July 2022

    I agree, the pains in my legs have a different not yet explanation from the one in my neck. I am sure of that much.
  14. Jonathan Edwards

    UK: Priority Setting Partnership: Medically Not Yet Explained Symptoms - 10 top priorities published July 2022

    I took the survey and gave them a piece of my mind/body/whatisname. I have had all their symptoms, not yet explained, but so what?
  15. Jonathan Edwards

    Coronavirus - worldwide spread and control

    We have another month to go! I had assumed that other European countries would make more costly mistakes by now but it seems that the virus is actually quite easy to control with reasonably non-draconian measures as long as you keep away from air transport, meat processing and night clubs. It...
  16. Jonathan Edwards

    Intelligence is negatively associated with the number of functional somatic symptoms, 2009, Kingma et al

    I think it may be important to consider the totally artificial context of these findings. A random selection of people were asked if they had various symptoms and been to see a doctor about them. I think it very unsurprising that less intelligent people would report more episodes of the doctor...
  17. Jonathan Edwards

    DecodeME - UK ME/CFS DNA study underway

    The protocol may well the best choice but I don't actually understand this statement: Those who pass the Canadian Consensus or Institute of Medicine criteria can participate. Following these criteria to the letter (as we will do) unfortunately means that those who are fully recovered will not...
  18. Jonathan Edwards

    The Times: Infectious diseases expert warns of spike in ME cases

    The policy document: https://www.england.nhs.uk/coronavirus/wp-content/uploads/sites/52/2020/06/C0388-after-care-needs-of-inpatients-recovering-from-covid-19-5-june-2020-1.pdf contains all the familiar BPS buzzwords including multidisciplinary and IAPT. There will be some practical work to do...
  19. Jonathan Edwards

    DecodeME - UK ME/CFS DNA study underway

    A GWAS study is something that, all things being equal, should be done. But all things aren't equal and I am not sure it's the very best use of $4million, given all of the clues screaming 'environmental factors.' That sounds very much like sour grapes to me. And what screams environmental...
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