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  1. Jonathan Edwards

    Coronavirus - worldwide spread and control

    We now have a coronavirus case in London. I suspect this will shift policy by tomorrow. I don't understand why Air China are still flying people in to UK.
  2. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    I am not so sure. On the train back from Switzerland we watched everyone touching their faces all the time and realised we did the same. But since sharing a queue with 500 people from Beijing I have realised just how close I may be to being infected and I have not touched my face today except...
  3. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    OK with me but I might get worried that if it goes on Facebook all the supermarkets will have empty shelves by tomorrow lunchtime! Fortunately we stocked up this afternoon.;)
  4. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    Don't worry, my wife and I went shopping this afternoon for the provisions we need and we will be pretty much self-isolating anyway. I think it very unlikely that there are any false positives for a specific RNA assay. This isn't like an antibody or T cell response test where normal and...
  5. Jonathan Edwards

    UK Times:'What if the thing that’s making you physically ill is your mind?', Feb 2020, Rumbelow [includes ME]

    I had forgotten - he was a co-author on the 1989 paper that claimed to be a speculative hypothesis paper about CBT for ME yet went on to say what should be done about 15 times (before any trials had been done). Perhaps the worst of all papers in the field.
  6. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    There would be no point testing me for virus now. My only likely contact was last night with some mask-wearing people from a Beijing flight. If a was infected I would not have detectable virus for a few days almost certainly. But I agree that not everyone is getting this right. I would score as...
  7. Jonathan Edwards

    What is the Functional / Organic Distinction Actually Doing in Psychiatry and Neurology? (Preprint, 2020) Bell, Greco et al

    This is pure plagiarism. I am sure it was in a Monty Python sketch in 1977 with John Cleese as Monica Streeb-Grebeling.
  8. Jonathan Edwards

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    I agree, deeply disappointing. By all means listen to what Dr B has to say but one could have hoped for a more enlightening comment.
  9. Jonathan Edwards

    UK Times:'What if the thing that’s making you physically ill is your mind?', Feb 2020, Rumbelow [includes ME]

    I had a peep. It is too dreadful to even register for this month's free peepie. I was quite interested by Thought for Today today on BBC Radio 4 Today. A regular lady priest was agonising over the issue of whistleblowers in the context of the Chinese doctor who reported the coronavirus and got...
  10. Jonathan Edwards

    UK Times:'What if the thing that’s making you physically ill is your mind?', Feb 2020, Rumbelow [includes ME]

    I am tempted to make a Wonko-style nonsensical observation here - but only to provide a sort of 'Amen chorus' to an eternal truth. I have visions of dung beetles pushing balls of pseudoscientific dung up a sand dune to feed their larvae dressed in blue cardigans and other assorted 'chattering...
  11. Jonathan Edwards

    Prevalence of functional somatic syndromes and bodily distress syndrome in the Danish population: the DanFunD study, 2019, Petersen et al

    Which makes me wonder why as a rheumatologist seeing hundreds of new patients a year for thirty years I can recall seeing no more than a dozen people who I now realise had ME/CFS. Maybe ME/CFS is not referred specifically to rheumatologists but at least I should have seen more people with CFS...
  12. Jonathan Edwards

    Coronavirus - worldwide spread and control

    Most micro-organisms do not survive more than a few minutes at 80 Celsius (176F). As I understand it viruses of this sort tend not to like being completely dried out and away from host environment for very long anyway. 100 Celsius kills almost anything (212F) except strange spore forming...
  13. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    I don't really understand your scepticism @large donner. This is a virus that produces pneumonia bad enough to require hospital care in maybe one person in seven affected. It may kill as many as one in fifty and maybe more because the death figures ahave to be compared with the diagnosis figures...
  14. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    Worth reading the Kekule blog mentioned by Leila. Mortality from regular flu seems to be about 0.1%. For the new coronavirus the figure looks to be about 2% but if this is underestimated because of lag in diagnosis to death it might be above 10%. Strangely the MRC have put out an estimate of 18%...
  15. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    That blog looks like an excellent and unbiased assessment. The only thing I would quibble with is the idea that wearing a mask might raise ungrounded fears. I see a much bigger problem with people forgetting to be careful. Thus, yesterday evening I arrived at Heathrow and had to queue for nearly...
  16. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    But Charles goes on to point out that things are getting more serious quite quickly. As I see it if everyone thinks that the risk is nearly zero then the virus is pretty well guaranteed to spread unnecessarily. I would personally advise everyone to take the risk seriously. I was amused to see...
  17. Jonathan Edwards

    BMJ Opinion: Peter Brindley and Matt Morgan: It’s time to be super heroes for scientific truth

    I am tempted to rephrase the old (unjustified as it was ) adage: Those who can understand science, do science. Those who can't become professors of the public understanding of science.
  18. Jonathan Edwards

    IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS, 2020, Hartwig et al

    I have not looked in detail but it seem as if they previously found a (very slight) increase in antibody levels to receptors in ME/CFS patients but now they find that these antibodies do nothing to the receptors, whereas ordinary people's antibodies do do something. That seems pretty confusing.
  19. Jonathan Edwards

    Potential benefits of a ketogenic diet to improve response and recovery from physical exertion in ME/CFS, 2020, Cossington et al

    If I remember correctly glycolysis means the oxygen-independent (anaerobic) breakdown of sugars to pyruvate. So it is not actually the 'burning' of sugar of aerobic respiration. I am not sure I can comment more usefully on the lactate results. Snow Leopard tends to be good on this.
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