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  1. rvallee

    Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews..., 2023, Kirkham et al

    A tool for inspection of RCTs (what about non-controlled ones? because there are tons of them in EBM) from Cochrane. Which looks to mostly involve asking people involved in so-called evidence-based medicine (EBM) what they think of EBM and whether their methods and reviews are good. Yeah...
  2. rvallee

    Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews..., 2023, Kirkham et al

    Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions Preprint: https://www.medrxiv.org/content/10.1101/2023.09.21.23295626v1 Abstract Introduction Randomised controlled trials (RCTs) inform...
  3. rvallee

    BPS attempts at psychologizing Long Covid

    At least temporarily, it's sad to say but Long Covid has actually set us back. I saw an article promoting GET in a local newspaper. Didn't bother reading it, it's always the same crap anyway. And here Knoop can just make stuff as much as he wants, everything they do is opaque and based on "trust...
  4. rvallee

    2012 Letter to the Independent on harassment of researchers

    Also, of course the allegations were false. The ones made by Wessely and his gang anyway. Allegations which later morphed into being trolled on the Internet, which even they walked back. And still the threats are repeated to this day, even though they were debunked.
  5. rvallee

    2012 Letter to the Independent on harassment of researchers

    He has? Because he made a few comments about his research some years ago, can't remember where, and he didn't have anything to mention other than he thought it was depression, then realized it isn't, even though this is what most MDs believe, and that they renamed it CFS, which is one of the...
  6. rvallee

    NICE and pain

    Yeah, but the chance of some contamination issues arising, either in the supply itself or during injection, is definitely not zero. These things happen. On a long enough timeline, they are guaranteed to happen to a significant absolute number of people, even if it's a small proportion. So this...
  7. rvallee

    Covid-19 vaccination experiences

    Ugh. Not feeling that great about having to get a vaccine update soon. I'll still do it, as some recent life changes mean I won't be able to remain clear of COVID, certainly not this winter, but this is really a lesser of two evils thing. Truly maddening that this is all because of...
  8. rvallee

    News from Aotearoa/New Zealand and the Pacific Islands

    Unfortunately, this is also actual medical advice you can get from MDs behind their desk in an actual clinic or hospital. And that is the most terrifying thing about it. It's as if geologists were going on about hollow Earth in their normal every day work, integrating it as part of it. Not in...
  9. rvallee

    News from Aotearoa/New Zealand and the Pacific Islands

    The whole framing about the solution being so damn simple, requiring no skills at all, all you have to do is to be open-minded, to not be such a downer ruminating about that illness-so-severe-it-left-you-bedbound-for-days that didn't even happen, since most cases stem from mild illnesses anyway...
  10. rvallee

    Opinion Lessons from a Neurologist After 25 Years of Functional Neurological Disorder Subspeciality Practice 2023 Stone

    These quacks sure do love to invent fake origin stories. Conversion disorder was invented by Freud and has been part of neurology since. It wasn't called FND, but that's about the only difference you could find with what fellow quack neurologists from a century were pushing. It's not even hard...
  11. rvallee

    International Journal of Molecular Sciences: Special Issue "Advances of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)"

    Saw this passing again and it seems that more articles have been published since, 8 in total. Research Evidence of a Novel Mitochondrial Signature in Systemic Sclerosis Patients with Chronic Fatigue Syndrome, Osman et al Circulating miRNAs Expression in Myalgic Encephalomyelitis/Chronic...
  12. rvallee

    Long Covid in the media and social media 2023

    Comes from this, at about 33 minutes: They are just completely lost and incapable of asking for directions. They can't even assess what they do properly. I never could have imagined that things were so bad, even with everything we knew of.
  13. rvallee

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    "Unplanned". Yeah this is the right word. We literally didn't know there was a "hiatus". Unplanned means it happens without warning, not that there is no communication whatsoever about it. Not even a word as to when this "hiatus" even began, how long it lasted, or any information. And it took...
  14. rvallee

    The course of self-perceived cognitive functioning among patients with lymphoma and the co-occurrence with fatigue and psychological distress

    Usually the case when you don't have any after having denied this issue for... ever. Even though: 15% Really? That's catastrophic. You're supposed to do the work if you want results. Don't do the work? No results. Do the work? Eventually you get results. They didn't do the work. Still aren't...
  15. rvallee

    Replication games: how to make reproducibility research more systematic, 2023, Brodeur et al

    Yeah that's been one of the biggest factors why things are so messed up in evidence-based medicine. Sharpe actually replied once to someone criticizing the many flaws in PACE that they should just run their own multimillion dollar trial that takes 10 years to complete. What a ridiculous troll...
  16. rvallee

    The relationship between self-reported chronic stress, physiological stress axis dysregulation and medically-unexplained symptoms 2023 Schulz et al

    They're presenting their hypothesis as highlights? I mean yeah, sure, someone is bound to try that but I guess the journals have just given up bothering to do their job? Just the same old correlations that work best as consequences presented as causes just because they prefer that. But the...
  17. rvallee

    Developing a blood cell-based diagnostic test for ME/CFS using peripheral blood mononuclear cells, 2023, Xu, Morten et al

    Heh, wasn't sure but thought so. I made the comment anyway because it's definitely a thing that comes up a lot, and why even though there is so much frustration going around about 'lazy diagnoses' making it easy to get free money, disability systems are really not likely to be bothered to do...
  18. rvallee

    “Your Blood is Black”: My ME/CFS Experience with HELP Apheresis in Germany

    That's what our human-lizard overlords want you to believe
  19. rvallee

    The Netherlands ME/CFS Cohort and Biobank (NMCB) consortium

    There's a case to make about rapid irritability and sour mood, something normal and expected while ill, exhausted and in pain, but I have zero confidence that people who don't believe there is an actual illness can make that difference. So it's all dependent on what they believe. Change the...
  20. rvallee

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    It may be annoying to deal with after a while, but don't underestimate the power that thousands of people can have in emphasizing the importance of something like this. Maybe it's different in medical academia, though I doubt it, but generally speaking researchers get very little attention for...
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