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  1. Sly Saint

    Article: Hibernating Bears Provide Clue to Preventing Serious Clots in Humans

    https://www.the-scientist.com/news-opinion/hibernating-bears-provide-clue-to-preventing-serious-clots-in-humans-71064 research paper (not full text) Sleep like a bear Reduced expression of a platelet protein protects against thrombosis during chronic immobilization...
  2. Sly Saint

    Hypothesis: inflammatory acid-base disruption underpins Long Covid 2023, van der Togt & Rossman

    The mechanism of Long Covid (Post-Acute Sequelae of COVID-19; PASC) is currently unknown, with no validated diagnostics or therapeutics. SARS-CoV-2 can cause disseminated infections that result in multi-system tissue damage, dysregulated inflammation, and cellular metabolic disruptions. The...
  3. Sly Saint

    Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised

    Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study Lucy E.M. Finnigan Mark Philip Cassar Margaret James Koziel Joel Pradines Hanan Lamlum Karim Azer et al...
  4. Sly Saint

    OpenAi's new ChatGPT

    Chronic Exhaustion Syndrome (CES) Chronic Fatigue Impairment Disorder (CFID) Post-Exertional Malaise Syndrome (PEMS) Immune Deficiency Fatigue Syndrome (IDFS) Neurogenic Exhaustion Syndrome (NES) Systemic Energy Conservation Disorder (SECD) Neuro-Immune Exhaustion Syndrome (NIES) Endurance...
  5. Sly Saint

    Research funding: Examples needed of ME research projects failing due to not getting funding

    Another angle is to look at how much research (biomedical) has relied on funding by patients. The MEA in the UK (might have some figures/examples), Invest in ME also might be able to provide examples. Solve might have some examples re the US. eta: just re-read your initial post. from a...
  6. Sly Saint

    The biology of coronavirus COVID-19 - including research and treatments

    New Covid variant sparks fear as India sees huge surge of infections New Covid variant sparks fear as India sees huge surge of infections (msn.com)
  7. Sly Saint

    Amanita muscaria extract potentiates production of proinflammatory cytokines by dsRNA-activated human microglia 2023, Wagner et al

    Recent interest in mushrooms and their components as potential therapies for mental health, along with recent government and health authority approvals, has necessitated a more comprehensive understanding of their effects on the cellular microenvironment of the brain. Amanita muscaria has been...
  8. Sly Saint

    Public Priorities in Women's Health: Analysis of Request for Information Published to Inform “Advancing NIH Research on the Health of Women

    Abstract Objectives: To assist with planning a congressionally requested conference on women's health research, the National Institutes of Health (NIH) Office of Research on Women's Health (ORWH) invited comments to characterize public concerns related to any or all of the specified public...
  9. Sly Saint

    USA: Cornell Center for Enervating NeuroImmune Disease and Maureen Hanson

    Merged thread full article https://news.cornell.edu/stories/2023/04/95m-fund-chronic-fatigue-syndrome-research
  10. Sly Saint

    Exercise Pathophysiology in ME/CFS and Post-Acute Sequelae of SARS-CoV-2: More in Common Than Not? 2023, Joseph, Systrom et al.

    ABSTRACT Topic Importance Post-Acute Sequelae of SARS-CoV-2 (PASC) is a long-term consequence of acute infection from coronavirus disease 2019 (COVID-19). Clinical overlap between PASC and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has been observed, with shared symptoms...
  11. Sly Saint

    Long Covid in the media and social media 2023

    judging by the replies to that post, his suggestion was not very well received. I was amazed to see he didn't know what FODMAPs are, nor apparently was he aware of the high oxalates in celery juice, and the potential effect on kidneys.
  12. Sly Saint

    Definition of Post–COVID-19 Condition Among Published Research Studies 2023,Chaichana et al.

    Introduction As of February 2023, there have been approximately 759 million confirmed cases of COVID-19 infections globally1 and some individuals have experienced persistent symptoms, such as fatigue and shortness of breath, after recovering from the initial illness from COVID-19. The UK...
  13. Sly Saint

    The Effects of Tailored Energy Preservation Training on Fatigue and Re-admission in Patients with Heart Failure: A Randomized Clinical Trial

    Abstract Background: Fatigue and re-admissions are the important consequences of heart failure that cause limitations in patients’ daily activities, personal, and social affairs. Energy conservation techniques are among evidence-based and non-pharmacological approaches that can reduce fatigue...
  14. Sly Saint

    Allodynia - Painful skin, general sensitivity

    Association of Migraine disorders (video presentation) S5:Ep4 – Allodynia and Migraine (full transcript at link) https://www.migrainedisorders.org/podcast/s5ep4-allodynia-and-migraine/
  15. Sly Saint

    Going long: Viruses linger with lasting impact

    By Diane Mapes, Fred Hutch Cancer center very long piece https://www.fredhutch.org/en/news/center-news/2023/04/viruses-linger-with-lasting-impact-hpv-hsv-hiv-long-covid.html
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