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  1. Sean

    Thesis Adaptation and validation of the Health Anxiety Inventory (short version) for medical settings, 2023, Colenutt

    Do they ever ask why people with serious chronic health conditions might be anxious, especially in a clinical or medico-legal setting?
  2. Sean

    Preliminary clinical and cost effectiveness of augmented depression therapy versus [CBT] for the treatment of anhedonic depression, 2023, Price et al

    Back in my (brief) uni days I shared a house with an ex-psychologist. He was ex because he said after a few years of clinical practice he realised that all he was doing was superficially patching people up (and often not even that much) and just sending them straight back out into the world...
  3. Sean

    Moderate Exercise Increases Expression for Sensory, Adrenergic, and Immune Genes in CFS Patients But Not in Normal Subjects 2009 Light et al

    After moderate exercise, CFS and CFS-FMS patients show enhanced gene expression for receptors detecting muscle metabolites Interesting.
  4. Sean

    Article: Despite Resistance, Policy Makers Push The Paradigm On ME/CFS And Long COVID - Hughes, Lubet and Tuller

    Great article, much thanks to the authors. :):hug: I agree, this is an important aspect to it. Overturning the old paradigm in this case was not driven by new evidence, but by a more honest look at the existing evidence, or lack of it.
  5. Sean

    UK Government ME/CFS Delivery Plan consultation

    "definable pathology has been identified" Not sure I would have said that. "The key diagnostic symptom of ME is PESE (Post Exertional Symptom Exacerbation)," Need to at least add (also known as PEM, Post Exertional Malaise). Lack of historical continuity is a problem. Anybody dealing with...
  6. Sean

    Lightning Process study in Norway - Given Ethics Approval February 2022

    On the other hand, motivation and a hope that the treatment will work is necessary for a psychoeducational method such as the one used in the study to be effective. The perfect excuse for failure: Blame the patient for not having the right attitude, before they even try the 'psychoeducation'...
  7. Sean

    UK Government ME/CFS Delivery Plan consultation

    5) Recognise that people with ME and their carers have experienced decades of marginalisation, discrimination, neglect, and often even a lack of compassion and understanding from some of the people they turn to for help. Including decades of vicious smear tactics and straight abuse. We are...
  8. Sean

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    Completely agree. I have not lost basic strength. I can still pick up heavy objects without much trouble. Being a largish male I could probably pick up more weight than most my age. But I have no stamina, and I pay a highly disproportionate physical price for picking up that weight...
  9. Sean

    German Government announces new funding guidelines for ME/CFS

    Not just the stats angle, but reanalysis in general.
  10. Sean

    The Chrysalis Effect

    :sick::sick::sick:
  11. Sean

    GPs ignoring cancer warning signs in young people, says UK oncology expert

    As many in this community long predicted would happen. Tip of the iceberg. No branch of medicine is going to be immune to this brazen power grab.
  12. Sean

    Trial Report Tonix's Long COVID Drug Fails to Meet Midstage Trial Goal

    Nice to see negative outcomes being reported honestly.
  13. Sean

    Structural and functional impairments of skeletal muscle in patients with [PASC], 2023, Colosio et al.

    the speed of adjustment of oxidative metabolism during transitions to moderate-intensity exercise (O2 kinetics) That is an interesting angle.
  14. Sean

    Gupta amygdala training program for ME/CFS, FM and Long Covid - news and discussion

    To test the efficacy of a novel and cutting-edge treatment known as the Gupta Program. The one you have been flogging for decades already? Therefore neither novel and cutting-edge, nor properly tested yet. Current literature points to a centrally sensitized state in CFS. No it doesn't.
  15. Sean

    Could Some Patients With Fibromyalgia Potentially Have Hypophosphatasia? A Retrospective Single-Center Study 2023 Injean et al

    I have the opposite, consistently high ALP every time it has been measured since I got ME. The most consistent (abnormal) lab finding in my medical history.
  16. Sean

    Hypothesis The viral origin of myalgic encephalomyelitis/chronic fatigue syndrome, 2023, Maureen R. Hanson

    @EndME Thanks. :thumbsup: Certainly not suggesting it is appropriate for regular clinical use. But a far earlier use of it for basic research could have saved us a lot of trouble, regardless of what it finds.
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