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I think vaccinations against variants will be necessary in the future. It might not be annually, but biennially (every two years).

Mutations are a stochastic process, so more vaccinations means less mutations due to reduction in cases! Vaccines can apply 'selection pressures' that can lead to vaccine escape mutations, but the virus seems to be becoming more virulent just fine without the help of vaccines.

Is this corneal nerve fibre loss associated with neuropathic eye pain?

Some Cognitive Behavioural Therapy will fix that nerve fibre loss, no problems!

This is modelling of vaccination impact in Australia "Race to 80: our best shot at living with COVID" https://grattan.edu.au/report/race-to-80/ https://grattan.edu.au/wp-content/uploads/2021/07/Race-to-80-Grattan-technical-supplement.pdf The headline figure is that we can open up once we reach...

This is my experience also. It is fatigue in the sense that effort required for a given level of mental performance increases rapidly until no amount of effort works and the mental ability just disappears. It is most revealing when doing an exam - you start off with some ability, but by the...

They are trying to measure sensitised pain pathways, (what they're really trying to say is the brain is overreacting to pain signals). But study results tend to be equivocal or inconsistent between studies. There has been many attempts to state and or try and prove that all "functional somatic...

Or it means the effect is too small to be detected with the given sample size. But if you need 100 people to demonstrate a small effect, chances are the intervention is almost useless anyway.

Why innovate when you can just perform the same studies again and again on slightly different patient groups, despite never having any actionable results?

It will "shock" us? I guess that suggests they are still ill.

The most insulting thing about the whole Opoids crackdown is that prescription rates have declined, yet there is no effect on opioid related deaths in the USA. (prescription rates are /10000) I don't see a cause and effect relationship there. data from...

For me, I had some improvement in the initial years, but it's been a slow but steady decline since then (including new symptoms). I'm not sure (specifically) what really accounts for the improvement, but I'd like to blame age and subsequent infections on the steady decline, even if it isn't true.

There is evidence of an acute (short term) effect on pain through conditioning of endorphins (which are an evolutionarily derived mechanism for us to escape danger when suffering from pain) and a similar effect for acute nausea. There are no other scientific effects. The claim that there is an...

Goals, Page 18. Why is it always Yoga? Of course the young ones these days are woke and will probably reply "No, I don't believe in cultural appropriation" when asked "Have you tried Yoga". ;)

I keep seeing UK people saying "but low deaths" therefore everything is fine, but the UK has had more deaths in the last 3 weeks than Australia has had in total throughout the entire pandemic. And the Australia has 37% of the population of the UK... Of course, even if just 1-2% of COVID cases...

We're having a 7 day lockdown over 3 community cases and guess what? It's worked.

Poor Ramil :(

It seems to be the much larger anti-lockdown "we need to live with the virus" crowd who frequently deny that long-covid is a thing, or think that everyone is going to magically recover 100% within a few months.

While there is no evidence for any sort of generalised increase in autoimmunity risk, you do agree that certain infections can trigger specific acute autoimmune syndromes? Such as Guillain Barre Syndrome and the various autoimmune throbocytopenia and thrombosis with thrombocytopenia syndromes...

The half life of most IgGs is between 7-21 days depending on subtype. While in principle, they can be excreted, most are broken down after being internalised by cells, for example pinocytosis by endothelial cells or receptor mediated internalisation. They can also be degraded by extracellular...