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  1. rvallee

    USA: The RECOVER Initiative - Long Covid research

    It has been reported that the RECOVER initiative has secured an additional $200M in funding for clinical trials.
  2. rvallee

    Long Covid in the media and social media 2023

    To discuss this, go to this thread: USA: The RECOVER Initiative - Long Covid research
  3. rvallee

    Long Covid in the media and social media 2023

    Hmmm. Works for me. What do you get instead? Oh I see that it's paywalled. I took the quotes from someone on twitter with access to it. Thread with many more quotes: https://nitter.net/ZurNull/status/1735158834795012445.
  4. rvallee

    Routine outcomes and evaluation of an 8-week outpatient multidisciplinary rehabilitative therapy program for FND 2023 Guy et al

    62% follow-up data. No controls or randomization, in fact there is a selection process. Retrospective evaluation. They're basically working around the most basic requirements of EBM by simply framing this as routine service evaluation from an existing clinic that assumes the treatments are...
  5. rvallee

    Long Covid in the media and social media 2023

    Business press continues to do a far better job covering the impacts of COVID. It affects the bottom line and productivity of companies everywhere. What companies can do against Long Covid Harvard Business Manager...
  6. rvallee

    News from Australia

  7. rvallee

    A taxonomy of threat and soothing influences in rheumatic and musculoskeletal diseases and central sensitivity syndromes 2023 Hijne et al

    Unfortunately, this is where the difference between book smart and smart lies. General intelligence is very hard to assess, and the entire schooling system pretty much ignores it, it's too diffuse, too hard to develop. It rewards people who are able to quickly answer questions, whether or not...
  8. rvallee

    CAR-T therapy

    ‘It’s all gone’: CAR-T therapy forces autoimmune diseases into remission https://www.nature.com/articles/d41586-023-03968-6 Engineered immune cells have given 15 people with once-debilitating autoimmune disorders a new lease on life, free from fresh symptoms or treatments. The results raise...
  9. rvallee

    A taxonomy of threat and soothing influences in rheumatic and musculoskeletal diseases and central sensitivity syndromes 2023 Hijne et al

    Generic fluff. People don't like bad things happening to them. People like good things happening to them. Groundbreaking stuff.
  10. rvallee

    Artificial intelligence in medicine and science

    ChatGPT outperforming human doctors in behavioral, cognitive, and psychological–related questions is both hilarious and not the least bit surprising. This is by far the weakest area in all medicine, and the gap will only grow wider. AIs don't read between the lines or see thinly veiled language...
  11. rvallee

    Artificial intelligence in medicine and science

    Performance of Large Language Models on a Neurology Board–Style Examination JAMA Neurology: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812620 Key Points Question What is the performance of large language models on neurology board–style examinations? Findings In this...
  12. rvallee

    Efficacy and Safety of Antidepressants in Patients With Comorbid Depression and Medical Diseases, 2023, Brasanac et al

    Posting this because it seems to continue the usual problem in evidence-based medicine where conclusions are simply not supported by their own data. This is a systematic review of systematic reviews, making a positive recommendation for SSRIs, despite acknowledging that there is no good...
  13. rvallee

    Efficacy and Safety of Antidepressants in Patients With Comorbid Depression and Medical Diseases, 2023, Brasanac et al

    Efficacy and Safety of Antidepressants in Patients With Comorbid Depression and Medical Diseases An Umbrella Systematic Review and Meta-Analysis JAMA Psychiatry: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2809163 Key Points Question What is the evidence for use of...
  14. rvallee

    Targeting persistent fatigue ... in adolescents and young adults with a fatigue syndrome or rheumatic condition... 2023 Vroegindeweij et al

    Poorly-run trial of two identical biased open label interventions finds no difference in outcomes: "yeah this is good I guess they're both great!". The entire methodology is built around comparing outcomes, itself fraught with issues, and they don't even bother with that. And all such "tailored"...
  15. rvallee

    Bridging Uncertainties: Exploring the Lived Experiences of Pediatric Long-COVID-19 Through ME/CFS Caregiver Narratives, 2024, Komalasari, book chapter

    The excessive focus on psychosocial does not inspire confidence. It's not what patients need. And it's not what patients want, because it's not what they need. Until there are disease-modifying treatments, this is always a waste of effort and resources. If anything, it's doctors who need...
  16. rvallee

    Experiences of Canadians with long-term symptoms following COVID-19, 2023, Kuang et al

    Moved post Tweet has a link to this week's StatCan report and shows this image:
  17. rvallee

    Experiences of Canadians with long-term symptoms following COVID-19, 2023, Kuang et al

    Several people noticed that last year's StatCan data reported 1.4M people with suspected Long Covid. This year's report is 3.5M, with 58% of those reporting to have ever had symptoms still have them. This image made the rounds and was roundly ridiculed by MDs, but it's tracking rather well...
  18. rvallee

    CDC Data Brief: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in Adults: United States, 2021–2022, 2023, Vahratian, Unger et al

    Probably a bit of that, but also mostly having to do with the "not otherwise explained by a known diagnosis" qualifier. Reaching their 70's, people usually have multiple diagnoses, and general fatigue can and will always be put down to ageing, regardless of the age of the patient.
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