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Whilst I'm not fully convinced by 2-day CPETs, I'm also very wary of some of the claims and understanding made with respect to PEM in Long-Covid. I've talked to several Long-Covid patients who've said they had PEM, but as it turned out some of them just got shortness of breath when they...

UTILITY OF 2-DAY CARDIOPULMONARY EXERCISE TESTING PROTOCOL IN LONG-HAUL COVID (LHC) PATIENTS: PRELIMINARY DATA Purpose: Long Haul COVID (LHC) patients have prominent symptoms of fatigue and exercise limitation. Comparisons have been made between Chronic Fatigue Syndrome/Myalgic...

The patients are taken from Merel Hellemonds clinic in Rotterdam (CO-FLOW cohort). The very big caviat is that all these patients were hospitalised (48.6% respectively 61.1% required ICU treatment, average hospital stay was 17.0 resp. 15.0 days) at the beginning of the pandemic. As such patients...

Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing fatigue severity Background: Many patients with SARS-CoV-2 infection develop long COVID with fatigue as one of the most disabling...

Translation of Tweet: There is news First post-COVID patients will be treated as of autumn 2023. Summary of website: reCOVer: BC-007 study starts. First post-COVID patients will be treated as of autumn 2023. reCOVer will be launching a Phase 2 (n=30) clinical research study into BC007 in...

I find this reasoning quite funny when it comes to Long Covid because there is an abundance of data on patients fully recovering from Covid, only to weeks later start experiencing Long Covid. Says a lot about the robustness of their model.

Thanks for sharing that, I wasn't aware of the patient feedback but had read these Tweets www.twitter.com/RobWust/status/1644202526235844609, www.twitter.com/RobWust/status/1650759252644962308, in defence of the LifeLines cohort, which might be very sensible if you aren't aware of the history of...

Here are some details @Solstice. Michele van Vugt is a clinical collaborator of Rob Wüst. She runs the Long Covid center at the Amsterdam UMC. See...

Upcoming symposium in Amsterdam on October 19 :https://turncovid.nl/covid-19-symposium/. Presenters include: Michele van Vugt, Brent Appelman, Jeroen den Dunnen, Merel Hellemons and Rene Lutter as well as a humor section by the well known Hans Knoop.

Unraveling brain fog in post-COVID syndrome: Relationship between subjective cognitive complaints and cognitive function, fatigue, and neuropsychiatric symptoms Abstract Background and purpose “Brain fog” is a frequent and disabling symptom that can occur after SARS-CoV-2 infection. However...

Indeed the monoclonal antibodies were adminstered in October and September 2021. The price of the drug doesn't seem to be too high either (at least compared to some other things) at roughly $1000 per person, from what I calculated. One would think they would have tried this on more patients by...

Influence of Prior SARS-CoV-2 Infection on COVID-19 Severity: Evidence from the National COVID Cohort Collaborative Background As SARS-CoV-2 has transitioned from a pandemic to endemic disease, the majority of new infections have been among previously infected individuals. To manage the risks...

A couple of months ago I read this news article https://www.news-medical.net/news/20230804/Genetic-reasons-behind-Raynauds-phenomenon-discovered.aspx. I suppose there would naturally be a significant overlap in the findings since there are overlaps in the biobanks. The news article also states...

Limitations and criticism of the HopeBiosciences trial can be found here: https://www.s4me.info/threads/usa-texas-long-covid-stem-cell-trial-hope-biosciences.33379/#post-475832.

Adipose-derived, autologous mesenchymal stem cell therapy for patients with post-COVID-19 syndrome: an intermediate-size expanded access program Abstract Background Evolving mutations of the novel coronavirus continue to fuel up the pandemic. The virus affects the human respiratory system along...

Similar to a previous study HERV-W and HERV-K again don’t seem to play a major role in ME/CFS (here they even seem to be downregulated in ME/CFS, FM and other comobidities). On the other hand a larger role was suggested in Covid and Long Covid...

Indeed the authors are not making this claim (I also wasn't trying to suggest that they were even though my post does definitely read that way), but I doubt the media or someone reading an article on it will interpret it that way. The question for me is what is the point of studying this so...

The problem is that the above research doesn't at all even try to look at longlasting Long-Covid or even anything related to ME/CFS (it essentially just looks at predominantly older patients to see whether someone had a cough or something else 4 weeks out). Whether the viruses that causes ME/CFS...

Virtual reality for assessing stereopsis performance and eye characteristics in Post-COVID Abstract In 2019, we faced a pandemic due to the coronavirus disease (COVID-19), with millions of confirmed cases and reported deaths. Even in recovered patients, symptoms can be persistent over weeks...

In my eyes this study would only be interesting if they would look at those patients with a low HRQoL (or multiple severe symptoms) multiple months post infections via a follow-up. The common long cold symptoms of cough, stomach pain and diarrhoea 4 weeks out are very uninteresting and mind I...