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Thank you for the response. A bit dissapointing that Hand grip strength, which played a bigger role in her new study as prognostic marker...

For the immunologists on this forum: Can anybody explain a more precise hypothesis why exactly Obinutuzumab is what Scheibenbogen is planning to accompany her Immunadsorption study with? From what I've understood Obinutuzumab is something like "the new Rituximab", with possibly some advantages...

SARS-CoV-2 Spike amyloid fibrils specifically and selectively accelerates amyloid fibril formation of human prion protein and the amyloid β peptide Abstract An increasing number of reports suggest an association between COVID-19 infection and initiation or acceleration of neurodegenerative...

Now that's funny. Didn't patients have to come up with the name Long-Covid because it was a new phenomenon nobody knew of and nobody was writing about, a community of patients meeting on Twitter? Did they believe in a disease that they didn't believe in? Now that news and scientists have started...

OMF funded study, for more information see: https://www.omf.ngo/HSE-publication/

Temporal pathway analysis of cerebrospinal fluid proteome in herpes simplex encephalitis ABSTRACT Objectives: We examined the temporal changes of the CSF proteome in patients with herpes simplex encephalitis (HSE) during the course of the disease, in relation to anti-N-methyl-D-aspartate...

A lot oft the big newspaper agencies have written something about the study. Science also wrote a piece https://www.science.org/content/article/clotting-proteins-linked-long-covid-s-brain-fog.

Haunting innate immune memories of COVID-19 In addition to acute hyperinflammatory responses, SARS-CoV-2 infections can have long-term effects on our immune system leading to, for example, post-acute sequelae of COVID-19 (PASC). In this issue of Cell, Cheong et al. show that severe infections...

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and subjective components. They are common and debilitating, and can affect the...

SARS-CoV-2 RNA Persists in the Central Nervous System of Non-Human Primates Despite Clinical Recovery Abstract Adverse neurological and psychiatric outcomes, collectively termed the post-acute sequelae of SARS-CoV-2 infection (PASC), persist in adults clinically recovered from COVID-19...

“Therefore, each subject to be diagnosed with ME/CFS must undergo a Fukuda criteria evaluation and procedure that each unit has established using batteries of validated self-administered questionnaires. “ “Patients were eligible to participate if they were 18 years, had a confirmed diagnosis of...

I remember when I went from full time working and high level athlete to fully bedbound within one night. I guess I just shouldn't have deconditioned so hard in that one night.

Dissecting human population variation in single-cell responses to SARS-CoV-2 Abstract Humans display substantial interindividual clinical variability after SARS-CoV-2 infection1,2,3, the genetic and immunological basis of which has begun to be deciphered4. However, the extent and drivers of...

The Netherlands seems to be the Wild West in terms of naming conventions. The BPS group calls it CVS and uses psychological criteria to diagnose it and then manipulates ME/CFS studies with that, they couldn't care less about guidelines. Then there's a misguided adovacy group that believes that...

Results contradict the previous study https://doi.org/10.1001/jamainternmed.2023.0743 discussed here https://www.s4me.info/threads/association-of-treatment-with-nirmatrelvir-and-the-risk-of-post–covid-19-condition-2023-yan-xie-phd-et-al.32483/#post-466630. However, the sample size is extremely...

Nirmatrelvir/ritonavir and risk of long COVID symptoms: A retrospective cohort study We conducted a retrospective cohort study to assess whether treatment with nirmatrelvir/ritonavir was associated with a reduced risk of long COVID. We enrolled 500 adults with confirmed SARS-CoV-2 who were...

Reactivated endogenous retroviruses promote protein aggregate spreading Abstract Prion-like spreading of protein misfolding is a characteristic of neurodegenerative diseases, but the exact mechanisms of intercellular protein aggregate dissemination remain unresolved. Evidence accumulates...

Haven't read anything of the study apart from the first word, which has been misspelled.

A novel flow cytometric method for detecting fibrin(ogen) amyloid microclots using long COVID as a model HIGHLIGTS Imaging flow cytometry utilizing a novel rapid flow cytometric detection method is a promising method for detecting amyloid fibrin(ogen) microclots in conditions associated with...

Agreed. I wanted to mention that all these patients seem to still be fit enough to partially work (at least that was the case for IDO2 study), were at least fit enough for hospital appointments 3 days in a row along with a bicycle test and have had Long-Covid for less than 1.5 years, so...