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  1. Jonathan Edwards

    Treatment suggestions for Orthostatic Intolerance (POTS or NMH)

    This is a reasonable question but we can also ask why homeopathy has been recommended for centuries when it does no good. The fact that lots of doctors recommend something is I am afraid not very useful. Doctors used to recommend tonsillectomies or spending six weeks in bed after heart attacks...
  2. Jonathan Edwards

    Introduction to Briggs Protocol for IBD

    Yup, this is just an advertising site.
  3. Jonathan Edwards

    Introduction to Briggs Protocol for IBD

    No, it has not been scientifically validated and since it has been around for at least thirty years that probably means there is nothing much to it. The general idea that ulcerative colitis, Crohn's and irritable bowel syndrome all stem from a similar leaky gut problem is quite clearly wrong...
  4. Jonathan Edwards

    Treatment suggestions for Orthostatic Intolerance (POTS or NMH)

    If POTS and NMH are due to poor autonomic regulation then I do not think it makes any sense to supplement with salt and water. The kidney will simply restore what it thinks is the 'right' volume but if the autonomic nervous system is not keeping vascular tone right then it is not going to be the...
  5. Jonathan Edwards

    Preprint: "Fallibility in science: Responding to errors in the work of oneself and others", 2017, Dorothy V Bishop

    Why does this lady think she is in a position to lecture other people about getting things right when she is so good at getting things wrong herself? Seems like teaching grandmothers to take the motes out of their eyes, to mix metaphors.
  6. Jonathan Edwards

    (Not a recommendation) Alastair Miller on CFS

    And by the way Dr Miller, psychotherapy does f*** all for rheumatoid arthritis - absolutely sweet Fanny Adams.
  7. Jonathan Edwards

    (Not a recommendation) Alastair Miller on CFS

    Sorry Dr Miller but you have clearly missed the point completely. CFS is unusual only in that poor clinical trial research is touted as being competent when it is not. Competent researchers in ME/CFS have no problem at all with patient 'activists', who value good quality research. It is not in...
  8. Jonathan Edwards

    Petition: Approve the use of IV saline for treatment in PoTS and M.E for NHS Scotland patients

    I don't follow that @MeSci. If the sodium level is low desmopressin is contraindicated. If it is normal there is no need to take any. If desmopressin is going to lower sodium levels then taking sodium will have no effect. With patients with inappropriate ADH secretion pouring sodium chloride...
  9. Jonathan Edwards

    A test of the adaptive network explanation of functional disorders using a machine learning analysis of symptoms, 2018, Melidis, Hyland et al

    Maybe, I certainly agree I may have been a bit quick to respond. But on further deliberation I am not sure I end up with a very different view. Highland says amongst other things: This paper presents the idea that diseases can be explained and treated with biological theories, mental illness...
  10. Jonathan Edwards

    A test of the adaptive network explanation of functional disorders using a machine learning analysis of symptoms, 2018, Melidis, Hyland et al

    I doubt there is much sense to be made. I suspect what they are proving is that diagnoses are made by people who use adaptive learning and sometimes go maladaptive. Its a bit like psychosomatic research I suppose - all in the heads of the researchers. Symptoms fall into certain clusters because...
  11. Jonathan Edwards

    Pinched Nerve in Neck...help!

    A pinched nerve would be expected to show some disc change on MRI but no spinal canal narrowing. The spinal canal is to do with the cord, not the nerves. So that makes sense. Pain affecting jaw and shoulder is a little unusual and suggests something like the third cervical nerve root. It is more...
  12. Jonathan Edwards

    Book due out: "Doing Harm: The Truth About How Bad Medicine and Lazy Science Leave Women Dismissed, Misdiagnosed, and Sick by Maya Dusenbery"

    We could do one of those papers with seventy three main authors and a subsidiary list of six hundred minor authors. We would need to make sure 55% of them were women though, to avoid flack.
  13. Jonathan Edwards

    Book due out: "Doing Harm: The Truth About How Bad Medicine and Lazy Science Leave Women Dismissed, Misdiagnosed, and Sick by Maya Dusenbery"

    I was thinking of something a bit like that. Whenever I have been seriously ill (cancer and stuff) I have benefited greatly from having my wife present scaring the pants off the doctor with difficult and pertinent questions.
  14. Jonathan Edwards

    Book due out: "Doing Harm: The Truth About How Bad Medicine and Lazy Science Leave Women Dismissed, Misdiagnosed, and Sick by Maya Dusenbery"

    Er, one could. Sadly, Einstein made virtually no contribution to science after his early papers. He spent decades trying to prove quantum theory was wrong. And in his final years he realised how much time he had wasted and that he was wrong.
  15. Jonathan Edwards

    Book due out: "Doing Harm: The Truth About How Bad Medicine and Lazy Science Leave Women Dismissed, Misdiagnosed, and Sick by Maya Dusenbery"

    Typical male chauvinist bias I would say. Why would the old men be better at cautionary tales than the old ladies? One man can teach six kids to fish so it does not matter if another five die off. The skills of motherhood are more one to one so grannies would be more useful. And since the women...
  16. Jonathan Edwards

    Environmental Exposures as a Potential Underlying Factor in Chronic Fatigue Syndrome; a Case Report (2017) Arseneau et al.

    There was never such a guarantee of reliability. The Lancet has historically prided itself on not being peer reviewed. It assumed that it was so important everyone would assume what it published was the best. It was never the case. But fifty years ago most articles submitted were of reasonable...
  17. Jonathan Edwards

    Environmental Exposures as a Potential Underlying Factor in Chronic Fatigue Syndrome; a Case Report (2017) Arseneau et al.

    I am afraid that this is not research or even an 'article' or a 'journal'. The only references to this 'journal' I can find are comments about it being a scam. The abstract tells us nothing and for some reason the 'patient' becomes 'patients'. The paper cannot possibly have passed any meaningful...
  18. Jonathan Edwards

    Which autoantibodies would you test for?

    Not sure I follow that. The exam seems to be a fashionable buzz word for 'everything'. It seems a bit like saying don't try climbing the Matterhorn, climb the world. Tough to know how to do that.
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