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  1. Sean

    Shingles vaccines, chickenpox, Shingrix

    Thanks a bunch, RFK Jr, and your batshit insane obsessions. What a legacy. :facepalm:
  2. Sean

    Effects of Cacao Flavonoids in Long COVID-19 Patients with Chronic Fatigue: FLALOC, a Placebo-Controlled Randomized Clinical Trial, 2026, Munguía+

    There are some weird people in the world. Such as those who need a scientific justification to eat chocolate without feeling guilty. :rolleyes:
  3. Sean

    Post-exertional malaise and the myth of cardiac deconditioning: rethinking the pathophysiology of long covid, 2026, Charlton, Wüst et al

    This is probably correct. At least some of what we might currently perceive as random is just insufficient understanding of the causal relationships driving it all. This. In fact we do it naturally, without planning, or motivating by an external force.
  4. Sean

    Post-exertional malaise and the myth of cardiac deconditioning: rethinking the pathophysiology of long covid, 2026, Charlton, Wüst et al

    This possibility was, of course, a bit of snark. If it were true then we would be self-healing instantly all the time and hence would not be sick!
  5. Sean

    Contested and neglected: Social and medical marginalization in severe Chronic Fatigue Syndrome, 2025, Nezamdoust & Ruel

    Given the right adjustments, people with ME/CFS, in all its categories of severity, possess capabilities that could be revived to a reasonable and necessary level of function for an elevated experience of life. As the social model of disability would argue, people with ME/CFS are not disabled...
  6. Sean

    Post-exertional malaise and the myth of cardiac deconditioning: rethinking the pathophysiology of long covid, 2026, Charlton, Wüst et al

    Indeed. The correct response to the oil pressure warning light coming on and the temperature gauge starting to rise is not to press the accelerator harder. I hope this paper is an anomaly. A (maybe even the) critical piece of evidence for lack of deconditioning (at least substantial enough to...
  7. Sean

    Post-exertional malaise and the myth of cardiac deconditioning: rethinking the pathophysiology of long covid, 2026, Charlton, Wüst et al

    Thresholds are a less problematic concept for me, as long as it is understood that they are dynamic and to some extent chaotic; not easy to spot, not a simple marker to avoid, more like a fuzzy space with a lot of inherent unpredictability; and not crossing a threshold doesn't mean you are...
  8. Sean

    Age at onset of narcolepsy in two large populations of patients in France and Quebec, 2001, Dauvilliers et al.

    I increasingly get the feeling that in general there are now sufficient clues sitting there in front of us, but we don't have the right conceptual framework yet to make the connections and draw a good research map.
  9. Sean

    EAPM 2025 (European Association Of Psychosomatic Medicine)

    Has he ever considered gathering sufficient robust evidence?
  10. Sean

    EAPM 2025 (European Association Of Psychosomatic Medicine)

    What most strikes me about the BPS movement is its lack of humility. They are utterly certain they are correct, and are instead entirely focused on how to market it to the lay public, the profession, and the political class.
  11. Sean

    Open Research study on ME/CFS and rest

    Convalescence is a concept and term that could be useful for us. Good chance, I think, that a lot more patients would do considerably better in the long term, even if not actually fully recovering, if they were both diagnosed early, and allowed to convalesce adequately in the early stages.
  12. Sean

    News from the USA, United States of America

    It is staring the medical profession and governments right in the face, and yet... *crickets*
  13. Sean

    SequenceME genetic study - from Oxford Nanopore Technologies, the University of Edinburgh and Action for ME

    It's pathetic, isn't it. They will not commit to the one thing that will help both us and their short-sighted budgetary obsessions, which is a solid basic research program. How many decades have been lost now because of this and the blocking of non-psych research by the psychs?
  14. Sean

    Anyone tried full-bed-width over bed tables?

    What angle is it (approx.)?
  15. Sean

    General thread on functional disorders in Denmark

    Damning with faint praise, indeed.
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