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Curious they used "persistent" as a qualifier in this context, perhaps even more so with Dr. Kim Lewis there. I'd gladly pay way too much to be seated at the same table as Nath, Hanson and Lewis. Persistence - or at least persisters -would likely have come up at some point. It's been my...

Is anyone really surprised?

You may be right. I was mildly taken aback at the thought the NIH at any meaningful level would suggest persistence. Could you help my brain reconcile your take with this other tweet that seems to suggest something different? I appreciate the handicap that trying to interpret tweets (vs the...

Were it only limited to that crew.

Bad lot, patients.

If this proves to be their finding, it may be important to remember this is the US. There likely will be major institutional resistance. Strike that. There will be depending on which pathogens they invite to the party. I don't want to get ahead of the results, though. But, yeah, politics and...

What an odd statement. If you embrace a persistent pathogen theory, how do you decide which pathogens can be at play, which cannot? That to me would seem one part huge undertaking, and one part dangerous politics.

I'm not sure we can declare that with certainty.

If their target audience was medical students, what better way to start teaching those future clinicians and researchers that it's "such patients" who present as an unstable challenge to "medical authority", than in a textbook, presumably used in medschool. The authors literally pit future...

Textbooks are more dangerous than studies or articles. Textbooks carry an implied imprimatur of codified authority. Perhaps more damaging, textbooks imprint. Then they endure as authenticated reference materials, from classrooms and lecture halls to home studies and bookshelves. Hard to...

I don't think they love us any more.

https://www.bayarealyme.org/blog/research-funded-by-bay-area-lyme-foundation-identifies-new-investigational-therapy-regimen-capable-of-irreversibly-damaging-lyme-bacteria-in-laboratory-tests/ In vitro tested, so early yet.

Which of course got its start in the US at the University of Rochester. :)

Yep. It's been on the table in the US for quite some time. I don't think it's made any noticeable dent in enough of the broad ME/CFS community to warrant any excitement at this point. It certainly did not help me. But it could be different elsewhere I suppose.

IMO, this may be the crux of the matter, the pivot point around which the debate spins. Can we trust the diagnostic metrics that historically have been brought to bear?

At the very least, in many cases, part of a tandem. In some, the whole story. Too many prohibitions against tissue testing, too much sketchy goings-on with regard to specific pathogens for comfort.

Yes. Extraordinary implications for a significant portion of "healthy individuals." Potentially.

In this example, are they speculating ME/CFS could be a channelopathy? I do realize it's just an example. but the emphasis on electrical variations could be consistent with a channelopathy, in theory. If so, it would be an acquired channelopathy. Well, at least in part.

What a thoroughly odd read. Left me with the feeling Fauci and the NIH never heard of Lyme disease. Or Bartonella. Or Babesiosis. Or....

For far too many, the healthcare sector doesn't and can't.