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  1. Forbin

    Biology for dummies

    From the Wikipedia article on the stomach. Nitroglycerin can be absorbed through the lining of the mouth.
  2. Forbin

    Weird NHS ME clinic referral form

    Well, here's one way to respond...
  3. Forbin

    Rethinking ME/CFS Diagnostic Reference Intervals via Machine Learning & Utility of Activin B for Defining Symptom Severity (2019) Lidbury et al.

    Wild guess - perhaps the test reflects "stability." Healthy controls and severe patients may both represent "stable" states (one of which is highly impaired). It might be that the patients that fall between these two extremes are "unstable," with the test results somehow reflecting that ongoing...
  4. Forbin

    'AI' extracts new knowledge from old science papers

    Or... just buy 72 of these 8TB hard drives for $120 a piece and create your own 576TB storage facility for about $8,600. :)
  5. Forbin

    BMJ Archives of Diseases in Childhood: ''Editor’s note on correction to Crawley et al. (2018)'', 2019, Nick Brown. (SMILE LP Trial)

    In a late 2017 article in Buzzfeed, she gives participant dissatisfaction as the reason for changing the primary outcome: But this correction says: Despite what further unpublished work might suggest, I somehow I doubt that the children would have underreported their attendance, compared to...
  6. Forbin

    Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    One of the Canadian Consensus Criteria is "marked weight change." In the first couple of months of the illness I lost about 15% of my body weight. I just seemed to have lost my appetite, perhaps influenced by the fact that eating often resulted in a "pounding heart" within just minutes. My...
  7. Forbin

    'AI' extracts new knowledge from old science papers

    The AI's going to be pretty frustrated when it gets to the PACE trial.
  8. Forbin

    Poll: Gastrointestinal symptoms

    About five months before the onset of ME, I had some pretty bad GI symptoms, including burning pain in the lower gut. They were severe enough to send me to a doctor (and it took a lot to get me to see a doctor back then). I was given "Librax," a sort of combination of drugs used to treat stomach...
  9. Forbin

    BMJ Archives of Diseases in Childhood: ''Editor’s note on correction to Crawley et al. (2018)'', 2019, Nick Brown. (SMILE LP Trial)

    I wonder what the cut-off level of their ingenuousness is. Were there a study in which a treatment was said to have turned ill participants into track stars, would a journal publish that result without objective evidence confirming the "self-reported" claims?
  10. Forbin

    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    Dr. Komaroff's online article in JAMA currently has about: 31,000 views. (07/12/19) 35,000 views. 42,000 views. 47,000 views. 65,000 views. (07/24/19) https://jamanetwork.com/journals/jama/fullarticle/2737854
  11. Forbin

    Suggest a name for Chris Ponting's ME GWAS project!

    I came up with this before I realized that the "S" in GWAS stands for "Study," not "Sequencing." "SEQUENCE ME" Darn. I even had t-shirts made :).
  12. Forbin

    Suggest a name for Chris Ponting's ME GWAS project!

    The ME-NOME Project. (?)
  13. Forbin

    Weighted blankets

    Though they are quite expensive, there are water-cooled/heated mattress pads. One I've seen is called the "Chilipad." An external unit heats/cools water that runs through tubing contained in a fabric "pad." I'm pretty sure you lie on top of the pad rather than under it, but it might make the...
  14. Forbin

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Induced by Repeated Forced Swimming in Mice, 2019, Hara et al

    One of the potentially stupid things I did in the wake of the severe upper respiratory infection I had (which began about three weeks before onset) was to resume my practice going for long bike rides in the evening, which typically left me drenched in sweat. I only did this once or twice during...
  15. Forbin

    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    Yeah - I fell ill in the US in 1983 and my doctors made no mention of "myalgic encephalomyelitis," even though my neurologist's summary contained the words "myalgia" and "possible encephalitis." I was left with the idea I had a poorly defined post-infectious condition which, hopefully, would...
  16. Forbin

    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    I may be wrong, but the Journal of the American Medical Association (published weekly) seems to be mainly aimed at physicians, some of whom would be researchers, but many of whom would not. I take Dr. Komaroff's article as intended primarily for physicians who see patients, and that its overall...
  17. Forbin

    Havana Syndrome: U.S. and Canadian diplomats targeted with possible weapon causing brain injury and neurological symptoms

    This is bad news for the diplomats. It can only mean that their symptoms are psychogenic.
  18. Forbin

    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    I was just referencing what other people on the board have said about the NEJM. I was surprised when I read it. I don't know if it's an official stance of the NEJM or just a de facto policy.
  19. Forbin

    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    I think you may mean "epidemic neuromyasthenia," not "epidemic neurasthenia." "Neurasthenia" was a 19th century diagnosis of people who were deemed to have been afflicted with the stresses of modern life in a post-industrial, urbanized world. Its popularity as a diagnosis had dwindled to almost...
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