Wild guess - perhaps the test reflects "stability." Healthy controls and severe patients may both represent "stable" states (one of which is highly impaired). It might be that the patients that fall between these two extremes are "unstable," with the test results somehow reflecting that ongoing...
In a late 2017 article in Buzzfeed, she gives participant dissatisfaction as the reason for changing the primary outcome:
But this correction says:
Despite what further unpublished work might suggest, I somehow I doubt that the children would have underreported their attendance, compared to...
One of the Canadian Consensus Criteria is "marked weight change."
In the first couple of months of the illness I lost about 15% of my body weight. I just seemed to have lost my appetite, perhaps influenced by the fact that eating often resulted in a "pounding heart" within just minutes. My...
About five months before the onset of ME, I had some pretty bad GI symptoms, including burning pain in the lower gut. They were severe enough to send me to a doctor (and it took a lot to get me to see a doctor back then). I was given "Librax," a sort of combination of drugs used to treat stomach...
I wonder what the cut-off level of their ingenuousness is. Were there a study in which a treatment was said to have turned ill participants into track stars, would a journal publish that result without objective evidence confirming the "self-reported" claims?
Though they are quite expensive, there are water-cooled/heated mattress pads. One I've seen is called the "Chilipad." An external unit heats/cools water that runs through tubing contained in a fabric "pad."
I'm pretty sure you lie on top of the pad rather than under it, but it might make the...
One of the potentially stupid things I did in the wake of the severe upper respiratory infection I had (which began about three weeks before onset) was to resume my practice going for long bike rides in the evening, which typically left me drenched in sweat. I only did this once or twice during...
Yeah - I fell ill in the US in 1983 and my doctors made no mention of "myalgic encephalomyelitis," even though my neurologist's summary contained the words "myalgia" and "possible encephalitis." I was left with the idea I had a poorly defined post-infectious condition which, hopefully, would...
I may be wrong, but the Journal of the American Medical Association (published weekly) seems to be mainly aimed at physicians, some of whom would be researchers, but many of whom would not.
I take Dr. Komaroff's article as intended primarily for physicians who see patients, and that its overall...
I was just referencing what other people on the board have said about the NEJM. I was surprised when I read it. I don't know if it's an official stance of the NEJM or just a de facto policy.
I think you may mean "epidemic neuromyasthenia," not "epidemic neurasthenia."
"Neurasthenia" was a 19th century diagnosis of people who were deemed to have been afflicted with the stresses of modern life in a post-industrial, urbanized world. Its popularity as a diagnosis had dwindled to almost...
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