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  1. forestglip

    Preprint Spironolactone for ME/CFS in a Patient Homozygous for rs5522 (I180V): A Case Report, 2026, Donnellan et al

    Could you please copy the specific information in the sequencing results which says TT is present at this location, and the documentation from the sequencing company that this interpretation is based on? I don't know why any sequencing company would report a T in this location for someone with...
  2. forestglip

    [HERVs] and [ME/CFS]:[...] Disease Pathogenesis, Immune Dysregulation, and as Potential Biomarkers and Therapeutic Targets, 2026, Perera, Carding+

    Human Endogenous Retroviruses and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Emerging Insights into Their Role in Disease Pathogenesis, Immune Dysregulation, and as Potential Biomarkers and Therapeutic Targets Perera, Krishani Dinali; Garcia, Elisa Oltra; Carding, Simon R. Abstract...
  3. forestglip

    Associations of physical fitness and choice reaction time with chronic fatigue in working-age adults: a population-based study, 2026, Ma et al

    I think whoever wrote the abstract skipped their correlation does not equal causation class.
  4. forestglip

    Associations of physical fitness and choice reaction time with chronic fatigue in working-age adults: a population-based study, 2026, Ma et al

    Associations of physical fitness and choice reaction time with chronic fatigue in working-age adults: a population-based study Background Chronic fatigue is prevalent among working-age adults and has been linked to reduced physical capacity and impaired cognitive performance. While...
  5. forestglip

    A crumb of a clue on epidemiology

    Yeah, it looks to be higher than in the US: Scottish Canadians Scottish Americans Also higher when considering the more general British ancestry: British Canadians British Americans If British ancestry were a risk factor for ME/CFS, then presumably we'd see a larger prevalence in...
  6. forestglip

    Preprint Persistent SARS-CoV-2 Spike is Associated with Localized Immune Dysregulation in Long COVID Gut Biopsies, 2026, Abraham Soria et al

    A new version was posted that no longer includes Amy Proal or Michael B. VanElzakker as authors.
  7. forestglip

    Elevated blood viscosity is associated with dysautonomia in long COVID symptoms, 2026, Tamariz et al

    Elevated blood viscosity is associated with dysautonomia in long COVID symptoms Background Long COVID is associated with elevated inflammatory and antibody levels. Elevated plasma proteins can increase blood viscosity and decrease blood flow. Our aim is to evaluate if blood viscosity is...
  8. forestglip

    Trial Report The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID, 2026, Reis et al

    They also published: Summary for Patients: Fluvoxamine and Metformin for Fatigue in Patients With Long COVID Web | DOI | PDF | Annals of Internal Medicine
  9. forestglip

    A crumb of a clue on epidemiology

    Yes, on Google Trends, you can pick Metro or City for the subregion option. Metro does make it more fine-grained into 210 areas, but the problem is that it becomes a lot harder to try to correlate it with other variables, since I think it'd be hard to find various stats like average income or...
  10. forestglip

    A crumb of a clue on epidemiology

    The geographic clustering is very distinct for ME/CFS searches. Here's a map for proportion of each state reporting Scottish ancestry calculated from the B04006 census dataset. It's also clearly highest in the same two general regions:
  11. forestglip

    A crumb of a clue on epidemiology

    It's kind of difficult to see the actual pattern among states on the Google Trends map for ME/CFS, so I made a map with much more contrast. The two upper corners of the country seem to have the highest scores for ME/CFS searches.
  12. forestglip

    Well-known, famous people with ME/CFS (public thread)

    Camisado highlighted the band Moodring in another thread: News article on the website Metal Injection: HUNTER YOUNG of MOODRING: "When I Get That Low, I'm Like, ‘Oh F*ck, What If I Don't Come Out Of This?’ Because Some People Don't.” Link
  13. forestglip

    ME/CFS Music

    I like it! Lyrics:
  14. forestglip

    Opinion Exploring duplication in reviews of Long COVID: 2020-2023, 2026, Raine et al

    Exploring duplication in reviews of Long COVID: 2020-2023 Gary Austin Raine; Claire Loise Khouja Background The unnecessary duplication of reviews is a recognised problem in the field of evidence synthesis. This paper reports findings from a study exploring potential duplication of effort in...
  15. forestglip

    A crumb of a clue on epidemiology

    Yeah, I think just too few searches from those countries. For example, for Greenland for the past day, it says "Hmm, your search doesn't have enough data to show here."
  16. forestglip

    A crumb of a clue on epidemiology

    I jotted down some quick notes from Wikipedia on what each of the meds above is primarily used for: I tried to look for cases of different drugs correlated in the same direction and which treat the same disease:
  17. forestglip

    A crumb of a clue on epidemiology

    Note the significant positive correlations with stimulants: - The amphetamines "Dextroamphetamine Sulfate Er" and "Adderall Xr" - "Methylphenidate Er" (Ritalin) States in which more people are prescribed stimulants are the states where more people search for ME/CFS, which seems to support the...
  18. forestglip

    A crumb of a clue on epidemiology

    I've been having some more fun with the search trends data trying to find what else it correlates to. Medicare is the health insurance provided by the US government. They provide state-level data for "The total number of unique Medicare Part D beneficiaries with at least one claim for the drug"...
  19. forestglip

    Trial Report The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID, 2026, Reis et al

    I think they did test that. It seems the results were similar for fluvoxamine whether they used the outcome of fatigue or depression.
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