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I had forgotten all about that thread which is why I could not follow what Andy and MEMarge were saying on yet another thread.

Rituximab does not deal with all B cell driven autoimmune diseases because it does not remove long lived plasma cells. In several autoimmune diseases autoantibodies are produced by short lived plasma cells, which die off, but that is not the case for all. Much more importantly the difference...

Just for fun I am wondering if King's College would feel it inappropriate for these other quacks to claim it as an institution of origin for the study. Some things are not worth the bother though.

Neither figure on the King's online staff list.

I have not read this but Simon's highlights seem to indicate the same old pernicious nonsense. Most of it is rationalisation designed to prove that the input of every member of the team is so important. (As opposed to admitting nobody has any idea what to do and has nothing to offer other than...

Interesting that this is an Elsevier product.

Interesting discussion. You (@MEMarge) and @Andy clearly know about certain smoke-filled rooms others have not found the door to. You might have said: The Nild-stocking Group haven't started the process of signing up grippers etc yet, but the MGM Determinator mentioned at a Herbaceous Group...

My mother has major internal inconsistency in her cognitive impairment. She knows who I am but doesn't know who I am. She knows where she lives but still wants to 'go home'. She has no idea there is an epidemic but she knows that Oxford will soon have a vaccine. And so on. She has advanced...

A point raised by Jo Cambridge that I did not mention is that a shift in VH (or IgHV) gene usage is not an indicator of clonal expansion as such. To identify clones you need to sequence the antigen binding section of the antibody (CDR or complementarity determining region).

I posted it.

I get it if I refresh once I have gone to the URL. Maybe the URL has been updated in some subtle way. I think I had better not respond. The poor girl should be having a relaxing dinner by now. Or should I? ;)

I wonder how history will recount all this.

Maybe not so small. Most of the improvement in PACE was seen in all groups with only a slightly bigger change for CBT and GET. At two and a half years all groups had improved - and to the same extent. My own suspicion is that with some chums on the committee that the authors of this paper will...

I wonder who wrote the response? Did Selena, in which case she at least knew the party line about the review. Was it her line manager? In either case, who then pulled it?

My comment seems to have disappeared. I was going to reply: I realise that you in a difficult position , Selena, but I hope that deep down you realise that I am not that dumb.

Google Dictionary seems to have got this sussed - even with a smidgin of tongue in cheek? The King's English: in the reign of a king, the term for Queen's English. So in the USA today that would be the right term? @dave30th

I saw a group of youngster munching Kentucky fried virus only yesterday.

There is a lesson here I think - about coincidences. They are uncommon. I was talking to my wife about this Cochrane business and it came to me again that although the exercise for CFS review might be seen as some trivial backwater in the affairs of Cochrane only of interest to a few nutters...

You wouldn't want to clone my knees and my back.

Who would have thought it.