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  1. Caroline Struthers

    Towards an institute for patient-led research - Trish Greenhalgh, BMJ blog November 12, 2019

    She's mates with Wessley. Worked together at Queen Mary?? Check this awful article out https://academic.oup.com/bmb/article/69/1/197/523356
  2. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Errr. Probably not. I think they get sent to at least the first author....
  3. Caroline Struthers

    HRA (Health Research Authority) & Bristol University's report on E. Crawley's CFS/ME Studies over registration to the Research Ethics Committee (2019)

    Do this panel of intelligent people not think that using school records to identify kids who miss a lot of school and then writing to their parents out of the blue to invite them to attend a "pilot" school clinic is something that should have ethical oversight? Where is a copy of the letters...
  4. Caroline Struthers

    Cochrane review: Homeopathy for treatment of irritable bowel syndrome, 2019, Peckham et al

    Yes. Good double blind trials of homeopathy as described above would be easy and cheap. The homeopathic medicine makers are rich and could fund these studies. Like pharma fund trials of their drugs because they have to get them licensed and so design them to favour the drug and spin the...
  5. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Finally finally after my having to remove any reference to the "P" word or the problems with the Exercise Review, and chase a couple of times, my not very rapid Rapid Response got published https://www.bmj.com/content/366/bmj.l4898/rr-3 woohoo!!!!!
  6. Caroline Struthers

    Bias due to a lack of blinding: a discussion

    The BMJ didn't publish my response even after I shortened it, so I posted it on my blog https://healthycontrolblog.wordpress.com/2019/09/30/comment-on-rob-2-a-revised-tool-for-assessing-risk-of-bias-in-randomised-trials/
  7. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Finally I submitted the rapid response to the BMJ and they didn't publish it!! I spent hours and hours honing it, and got some excellent feedback which improved it immensely, so that was a bit annoying. So I posted it on my blog...and tagged @jonathanasterne...
  8. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Thank you so much for this fantastic and clear explanation The trouble with the risk of bias tool is that the judgements are, at the end of the day, subjective (as we well know!). When these judgements are presented in individual reviews in a nice clear traffic light picture, the impression...
  9. Caroline Struthers

    Bias due to a lack of blinding: a discussion

    I am @Healthy_Control and found this excellent new thread just now without even being tagged! I have just submitted the following as a rapid response to the Risk of Bias 2 paper in the BMJ. It's amazing to see Sterne was PI on the 2012 paper... At the end of 2013 there was a debate held at...
  10. Caroline Struthers

    A Messiah in the Norwegian health system? Lightning Process and the Norwegian medical establishment - Blogpost by Nina E. Steinkopf (2019)

    Exactly right. But their reputation is as an incorruptible infallible group of independent scientists. The people with real power in the organisation are not scientists and they trust their volunteers to get it right. If the volunteer authors screw up due to incompetence or conflict of interest...
  11. Caroline Struthers

    A Messiah in the Norwegian health system? Lightning Process and the Norwegian medical establishment - Blogpost by Nina E. Steinkopf (2019)

    Yes! I used to work for Cochrane and realised after a few months that they are ideally placed to do the job. They have thousands of willing volunteers who could do the systemativ surveillance work. But they spend all their time training people to shoehorn dodgy data into meta-analyses which (as...
  12. Caroline Struthers

    A Messiah in the Norwegian health system? Lightning Process and the Norwegian medical establishment - Blogpost by Nina E. Steinkopf (2019)

    I agree totally. They always say "hope to reduce potential for bias" so they cannot be held responsible or actually police what people do. It's exactly the same as the trials registers - no guarantee of research quality. I would love to set up a Research Police Force/Ombudsman. Like a souped...
  13. Caroline Struthers

    A Messiah in the Norwegian health system? Lightning Process and the Norwegian medical establishment - Blogpost by Nina E. Steinkopf (2019)

    It's because the database of review protocols PROSPERO (https://www.crd.york.ac.uk/PROSPERO/) is supported by NIHR money I think. The NIHR have no control over who registers their protocols. I see from 1 October they are requiring people register their protocols before they have collected any...
  14. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    It will not affect the revision which is currently still under consideration. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003200.pub7/information#whatsNew 17 June 2019 Amended Addition of new published note 'Cochrane’s Editor in Chief has received the revised version of the...
  15. Caroline Struthers

    ME/CFS success story: Lightning Process on Youtube 2019

    I just had a look and disliked it. As you say, the number of likes and dislikes is not showing, and there are maybe one or two short negative comments (not yours) but the majority are positive and refer to negative comments you can no longer see. Awful.
  16. Caroline Struthers

    The People’s Trial: your chance to be a scientist in a fun online trial - 6 Aug 2019

    There is another person from Cochrane on the team. Anna Noel-Storr the person behind Cochrane Crowd.
  17. Caroline Struthers

    New poor Guardian article "ME and the perils of internet activism" 28th July 2019

    Blimey. Yes you're right. Doesn't time fly when you're enjoying yourself?!
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