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  1. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    In the paper they write: "Both the autonomic and central motor dysfunction result in a reduction in physical activity. With time, the reduction...
    Post by: Sam Carter, Mar 12, 2024 in forum: ME/CFS research
  2. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Isn't this the key rebuttal? As in, if the effort preference of a good chunk of ME patients is no different to the healthies (and in many cases...
    Post by: Sam Carter, Mar 12, 2024 in forum: ME/CFS research
  3. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    There's one tiny typo in an otherwise fantastic letter @ME/CFS Skeptic, "Walit" should be "Walitt".
    Post by: Sam Carter, Mar 11, 2024 in forum: ME/CFS research
  4. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I looked and couldn't find any code for the EEfRT analysis. It would be great if someone could find it. It does say under "Statistical analysis...
    Post by: Sam Carter, Mar 7, 2024 in forum: ME/CFS research
  5. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    The PIs write in the main paper that "The primary measure of the EEfRT task is Proportion of Hard Task Choices (effort preference)." Do they give...
    Post by: Sam Carter, Mar 7, 2024 in forum: ME/CFS research
  6. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    > Persons with PI-ME/CFS were more likely to choose the easy task over the hard task compared to the healthy volunteers. But if you can't do the...
    Post by: Sam Carter, Mar 7, 2024 in forum: ME/CFS research
  7. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    One way to think about it is that it's almost as though HVF was playing by a different set of rules. There's an implicit rule, I think, that...
    Post by: Sam Carter, Mar 6, 2024 in forum: ME/CFS research
  8. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Curiouser and curiouser. Before the clock started ticking each participant (I think) got four trial runs (they're marked as trials -4, -3, -2 and...
    Post by: Sam Carter, Feb 29, 2024 in forum: ME/CFS research
  9. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Healthy volunteer F was indeed a highly atypical button presser(!), and I can see why the investigators treated his data with caution. If you...
    Post by: Sam Carter, Feb 29, 2024 in forum: ME/CFS research
  10. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I've been trying to work out what the optimal play is given the rules of the game. I think it would be something like this: since your actual...
    Post by: Sam Carter, Feb 28, 2024 in forum: ME/CFS research
  11. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    From Worth the ‘EEfRT’? The Effort Expenditure for Rewards Task as an Objective Measure of Motivation and Anhedonia Treadway et al: ... For...
    Post by: Sam Carter, Feb 28, 2024 in forum: ME/CFS research
  12. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    It's never explicitly stated, but if you look in the supplementary data on page 9 of the file titled 41467_2024_45107_MOESM1_ESM.pdf there's a...
    Post by: Sam Carter, Feb 28, 2024 in forum: ME/CFS research
  13. Sam Carter
    Post

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Isn't it because the reward value for the easy task is always lower than the reward value for the hard task (with the probability of winning being...
    Post by: Sam Carter, Feb 28, 2024 in forum: ME/CFS research
  14. Sam Carter
    Post

    Insular cortex neurons encode and retrieve specific immune responses, 2021, Tamar Koren et al.

    Here's a linky to the preprint fulltext on bioRxiv: Remembering immunity: Neuronal ensembles in the insular cortex encode and retrieve specific...
    Post by: Sam Carter, Nov 10, 2021 in forum: Other health news and research
  15. Sam Carter
    Post

    FINE trial patient booklet 29/04/05 Pauline Powell

    Sorry @Lucibee, I can't do any better than Michiel and others further back in the thread. The only documents I can access are the Patient PR...
    Post by: Sam Carter, Aug 23, 2021 in forum: Psychosomatic news - ME/CFS and Long Covid
  16. Sam Carter
    Post

    Twitter issues

    I've also had this problem with Twitter and Firefox but it goes away if I open the link in a private window -- right click "Open Link In New...
    Post by: Sam Carter, Aug 17, 2021 in forum: General Advocacy Discussions
  17. Sam Carter
    Post

    Efficacy of therapist-delivered transdiagnostic CBT for patients with persistent physical symptoms in secondary care: an RCT, 2021, Chalder et al

    I think there are two PRINCE trials? PRINCE primary (as in primary care) and the one above, PRINCE secondary.
    Post by: Sam Carter, Jun 7, 2021 in forum: Psychosomatic research - ME/CFS and Long Covid
  18. Sam Carter
    Post

    France: Bio-Modelling Systems to start phase II clinical trial(s)

    @Trish, I think their treatment is one (or more) of a grab-bag of common psychotropic drugs given in conjunction with a "connexin-blocking agent"...
    Post by: Sam Carter, May 31, 2020 in forum: ME/CFS research news
  19. Sam Carter
    Post

    Protocol: Persistent physical symptoms reduction intervention: a system change and evaluation (PRINCE), 2015 onwards, Chalder, Moss-Morris, et al

    Linkies: Therapist Manual -- ACTIB Trial Patient Manual -- ACTIB Trial
    Post by: Sam Carter, Jan 24, 2020 in forum: Psychosomatic research - ME/CFS and Long Covid
  20. Sam Carter
    Post

    B-Lymphocyte Depletion in Patients With ME/cfs: A Randomized, Double-Blind, Placebo-Controlled Trial (2019) Fluge et al

    Am I right in thinking that the results of the three substudies mentioned in the trial's protocol have not been published? Even if there were no...
    Post by: Sam Carter, Aug 11, 2019 in forum: ME/CFS research
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