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  1. Mij

    Amino acids as a substitute for impaired ATP production

    He doesn't have ME, he is diabetic. He lost power in his wrist/hand while playing table tennis and it reminded me of losing power when I have delayed PEM.
  2. Mij

    Amino acids as a substitute for impaired ATP production

    Yes he is still taking XTend and has tried other formulas from Xtend, but finds the Lemon -Squeeze more tasteful and works better for him.
  3. Mij

    Amino acids as a substitute for impaired ATP production

    There are several different formulas for XTend. I prefer the BCAA Lemon-Lime Squeeze. I have to buy it from the US (iHerb) because they don't sell this particular formula in Canada. My diabetic friend who plays high-intensity table tennis swears by it. Years ago he couldn't hold the...
  4. Mij

    Amino acids as a substitute for impaired ATP production

    @salin No, it was 25 years ago. The formula also included vitamins.
  5. Mij

    Amino acids as a substitute for impaired ATP production

    I had a whole panel of amino acids tested and was below normal/low for many of them. The biochemist prepared a 'custom formula' that I took for 2 months with zero results.
  6. Mij

    UCalgary-led study reveals a genetic factor behind who may and may not benefit from opioids prescribed for pain

    Findings from international and cross-faculty collaboration provide insight on responses, including why some people may be at higher risk of dependency “Our work highlights the importance of taking each patient’s genetic makeup into account when making medical decisions,” says Dr. Heather...
  7. Mij

    Antigen specificity of clonally enriched CD8+ T cells in multiple sclerosis, 2026, Fumie Hayashi et al

    Abstract CD8+ T cells are the dominant clonally expanded lymphocyte population in multiple sclerosis (MS) lesions but their clonal identity, function and antigen specificity are not well understood. A comprehensive single-cell RNA-sequencing and T cell receptor-sequencing analysis of the...
  8. Mij

    News from Canada

    Some doctors caution against full-body MRI's as celebrity endorsements drive up demand "Doctors warn full-body MRIS supporting evidence ay put additional pressure on public health system" "After a bout of prostate cancer, Don Garnier wanted to take a more proactive approach to his health...
  9. Mij

    Problems arising for pwME from additional diagnoses of MCAS, hEDS and POTS. Advocacy discussion.

    It's a clinic in Toronto that most likely opened up business from messages they read on social media? "NOTE: If you’re dealing with CHRONIC or COMPLEX issues involving multiple systems or body regions (e.g. long-standing pain, neurological, hormonal, or autoimmune concerns), please select Dr...
  10. Mij

    Problems arising for pwME from additional diagnoses of MCAS, hEDS and POTS. Advocacy discussion.

    Chronic Fatigue Syndrome (ME/CFS) MCAS and ME/CFS often overlap. Mast cell mediators can disrupt sleep, lower energy, impair mitochondrial function, and increase inflammatory load. Treating MCAS may reduce post-exertional crashes and brain fog in CFS patients.
  11. Mij

    Problems arising for pwME from additional diagnoses of MCAS, hEDS and POTS. Advocacy discussion.

    Well MCAS has been taken over by naturopaths here in Canada and now referring to it as a 'comorbidity' to ME/CFS. MCAS, "unmasking a root cause approach that is widely misunderstood" example Do we want this?
  12. Mij

    Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender, 2025, Huang et al.

    Lactate-driven mitochondrial pretenders hijack hippocampal function after excessive exercise Huang et al.1 show a J-shaped relationship between vigorous activity and cognitive decline, with maximal benefit ∼1,000–1,300 MET-min/week and harm with excessive exercise. Using UK Biobank data...
  13. Mij

    EBV Dysregulation Is Associated With Immune Imbalance in Multiple Sclerosis, 2026, Chiara Meloni et al

    Abstract Background and Objectives Epstein-Barr virus (EBV) infection is a prerequisite for the development of multiple sclerosis (MS), yet whether EBV acts merely as a trigger at disease onset or also contributes to immune dysregulation and disease progression remains unclear. To explore...
  14. Mij

    News from Canada

    Flu season (yellow) is winding down in Canada after a really difficult December/early January. RSV (red) is now rising later in the season, while COVID (blue) remains relatively flat, possibly picking up in the spring.
  15. Mij

    General paresis of the insane: a diagnosis not to forget, 2025, Masud Husain

    There was speculation that Florence Nightingale was believed to have suffered from ME. but later diagnosed with possible brucellosis or tertiary syphilis.
  16. Mij

    Outcomes of ME/CFS Following Infectious Mononucleosis: Seven-year Follow-up of a Prospective Study, 2026, Jason et al

    But if we all experience severe delayed PEM, than how do we measure 'severe ME'? Some pwME have a predispositions to comorbidities.
  17. Mij

    Was our ME/CFS inevitable?

    I was never sick in my life before I got a viral infection at age 29 that developed into ME.
  18. Mij

    Was our ME/CFS inevitable?

    My sister who is six years younger than me developed Hashimoto. My sudden viral onset attacked my thyroid, I had 'extremely' elevated anti-thyroid antibodies and I got ME. Thyroid scan indicated my thyroid function was normal.
  19. Mij

    Self-reported Tinnitus and Vertigo or Dizziness in a Cohort of Adult Long COVID Patients, 2022, Degen et al

    The site also says this: Average duration in months Research shows Long COVID dizziness persists an average of 43 weeks (approximately 10 months) after initial infection. My dizziness/PVFS lasted 9 months after vertigo onset and thought I had recovered and returned to work, but I relapsed and...
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