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There’s been an interesting webinar hosted by Altmetric today, called “The Online Life of Retracted Science: the news cycle, social media and journalistic responsibilities” Here’s a webpage with all the posts from a live thread summarising what was discussed. Full video and slides will be...

Ah, interesting. I wondered about different NK cell subtype populations but hadn’t twigged that. There seems to be some discussion of more long lived NK cells in some papers, particularly in certain tissues or in these ‘memory’ NK cells? I’m not sure how that compares to other long lived immune...

While looking at CD38 involvement I also came across this paper which seems to indicate expression of CD38 is similar on both but bright have more of a regulatory role which is influenced by CD38 pathways. I can’t access it unfortunately but from the abstract it looks like it could also be...

Thanks. Oh well, guess we can’t have everything. It sounds like it’ll all still be good useful info.

Also this from the Introduction Not sure what it all means! Wiser minds may want to chip in. But I found the different types of NK cells and the tissues they lurk in interesting. There’s also some papers on their potential role in neurological conditions.

Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus Abstract Summary Natural killer (NK) cells belong to the innate immune system but can also affect adaptive immune reactions. This immune regulatory function is often ascribed to the...

Nice work introducing them @ryanc97 will be interesting to see what they turn up. Do you know if he/they are also looking at NK cells themselves? We’ve talked before about the idea of memory in the innate immune system as well as the adaptive, there seems to be increasing discussion of memory...

Well put @Trish I guess it’s like the difference between weather and climate when we have a new big storm and how much influence climate had on it. We cannot and don’t think we should blame a single poor decision on people like Wessely (I don’t think they always have as much power to make...

Yes please. We could do with some divine intervention.

I was dissecting this but what’s the point. It’s all nonsense. Do they mean three hundred thousand or 3000 in the region or what? The county has abysmal support. The NHS service is worse than useless. There are no charities representing us in the region.

It shows many MPs will happily sign up to anything to look like they’re doing something, with little understanding of what they’re putting their name to. I’d hope their constituents can help inform them. Maybe if anyone reading this is, they can send their MP the BACME letter?

I agree this sounds most likely. A combination of not seeing something as a priority and organisational issues (inertia and restructuring). It’s a pattern that crops up for problems in many organisations, you don’t meed a Wessely for a such a systemic failure to occur.

Editing/removing post as got my names confused! Bezisterim is a synthetic analogue of androstenetriol Which is different from androstenediol (or indeed androstenedione) Brain not coping well with parsing the diols and triols and diones, is there a trione? Why yes there is! They all seem...

Amazing amount of work @forestglip and I love the safe form of self experimentation and ingenuity/creativity involved. I can understand some disappointment at finding no significant associations but am sure and hope you took something positive from the exercise. No doubt a few things learnt in...

Thanks Simon, fingers crossed. The offer is still there if a plain text or even just a more parseable format like latex is available.

@Simon M @chillier this looks really interesting, is there a more accessible format of the paper available anywhere or can someone provide the plain text so I can create an audio version? It looks like there’s only the PDF and it is sadly formatted in way which makes screen readers or other...

I was prescribed Zopiclone and used it for a short period very successfully without problems for a period before my ME/CFS. When I began having serious sleep problems with my ME/CFS I tried it again, it was a very different experience and didn’t go well. I got some bad advice from a Dr and...

Clearly a huge amount of work here @ME/CFS Science Blog thank you! I’ll be going through this properly in the coming days. Looks like a really good resource to have.

Nice work @Eleanor will share and see of we can get some more donations for you and all of us!

Interesting. I seem to remember the platform SequenceME plans on using includes methylation info https://nanoporetech.com/platform