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Abstract 6275: Multidimensional analyses of pedigree, epidemiologic, and molecular data provide etiologic clues for myalgic encephalomyelitis/chronic fatigue syndrome. Moslehi, Roxana; Kumar, Anil; Dzutsev, Amiran [Line breaks added] Background Myalgic encephalomyelitis (ME)/chronic fatigue...

I was wondering about the genetics too. One way I was thinking of going about it was, if we assume the DecodeME regions cause ME/CFS, and if we assume being British increases risk of having ME/CFS, then we might expect that one or more of the DecodeME variants might be found more often in...

That's surprising, since the correlation seemed large for both prescription of alcohol addiction drugs as well as deaths due to alcohol from a totally different source. Not only that, but I also ran correlations against around 2800 more variables from a third source, the Correlates of State...

Thread for the study: A Comprehensive Examination of Severely Ill ME/CFS Patients, 2021, Chang et al

An abstract about ME/CFS guidelines has been moved to a new thread: Physical activity for myalgic encephalomyelitis/chronic fatigue syndrome: A clinical practice guideline, 2026, Kirsh et al

It occurs to me that the p-values I've reported for the correlations are probably not totally valid, since the observational units being tested here (states) are not really independent from each other. For example, states near each other will tend to be more similar to each other than to far...

Intriguing...I found another variable (with the help of some brainstorming with AI) that clusters in the two upper corners: higher physical activity. - https://www.worldlifeexpectancy.com/explore/usa/physical-activity-regular/map The data from that map is at this link. I did a quick linear...

Whispers in the Dark: A Critical-Creative Exploration of Lived Experiences of Myalgic Encephalomyelitis (M.E) and Long Covid Based on a Collaborative Audiobook Listening Practice Jackson, Arlene Abstract This thesis is composed of two parts: a novel, Dear Listener, and a critical commentary...

Several posts specifically about the ECHO learning modules have been moved to Long COVID & Post Infectious Syndrome ECHO sessions (University of Utah)

As a sensitivity check to see how much the changes in Google Trends data downloaded on different days would affect the correlations, I redid the above cause of death correlation analysis, but with the re-downloaded Google Trends ME/CFS data for the same time span (2004/01/01 - 2026/03/24)...

Description of a Case with Multiple Chemical Sensitivity in Combination with Neurotoxic Disease and Chronic Fatigue Syndrome Hill, Hans- Ulrich; Huber, Wolfgang Abstract Here we present a case of a lady, called Mrs. P., a shop assistant of a wholesale market for agricultural device and...

DHCR7 Mutation Carriers and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: No Associations According to DecodeME Data Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multi-system disorder whose pathogenesis is associated with metabolic and immune...

See also: Cross-disorder comparison of brain structures among 4836 individuals with mental disorders and controls utilizing danish population-based clinical MRI scans (2026, Molecular Psychiatry)

The largest effect size was reduced thalamus volume. See also a recent long COVID paper: Association of structural brain changes with cognitive deficits and fatigue in patients with post COVID-19 condition (2026, Brain Communications)

Cross-disorder comparison of brain structures among 4836 individuals with mental disorders and controls utilizing danish population-based clinical MRI scans Abstract Large-scale mega-analyses of worldwide combined Magnetic Resonance Imaging (MRI) studies have demonstrated brain differences...

Moving right along in our data mining operation... CDC Wonder is a website which provides access to several interesting public health datasets. I downloaded age-standardized rates of causes of death grouped by state from the Multiple Cause of Death 1999 - 2020 dataset. This dataset gives the...

One slightly frustrating thing about Google Trends is that the data does not appear to be consistent if downloaded on different days, even if representing the same time span and search term. The 22 year data for ME/CFS I was using was downloaded on 2026-03-24, and represents the time span of...

The paragraph above is referring to the top left plot. Seems like it could be interesting, but the p-value isn't very low, and from the plot it looks like there were only two people in the mild group and two people in the severe group for this test. The other three plots were based on a more...

I again ask that you provide the reason you think that T reported by 23andME or any other company would mean translation into valine, because this doesn't seem to make sense. There is no thymine (T) molecule at this location in the DNA on either strand if valine is included in the protein...

Technically, for Metformin, the use they're recommending is for preventing long COVID before it starts, not for symptom reduction in already sick people.