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My mistake, I just looked at the video from last year, and it's the same plot. Timestamped link.

Some notes on Morgane Bomsel's talk: This is about patients with symptoms more than 6 months after acute COVID, and median 16 months after. She showed a plot of SARS-CoV-2 detected in megakaryocytes which is the same as the one shown last year: Around 30% of megakaryocytes in long COVID have...

I might be misunderstanding something, but doesn't NIH have a budget of around $1.5 billion for long COVID over about a decade? https://thesicktimes.org/2024/12/12/nih-announces-147-million-in-additional-long-covid-research-funding-new-budget-details/

Abstract 4344995: Prognostic value of cardiac computed tomography delayed enhancement in individuals with post-acute sequelae of COVID-19 [Line breaks added] Introduction/Background Post-acute sequelae of COVID-19 (PASC) have been recognized as serious complications of SARS-CoV-2 infection...

Abstract 4369416: Impact of Long COVID on Physical Activity and Sleep: a Matched Cohort Study using Wearable and EHR data From The All of Us Research Program [Line breaks added] Backround Long COVID (LC) is associated with negative health effects, but its impact on health behaviors such as...

As far as I can tell, this is just a poster abstract. There's no more text behind a paywall.

FYI, the full texts of paywalled Nature papers are often available on PubMed Central: https://pmc.ncbi.nlm.nih.gov/articles/PMC7572537/

There's a website to explore a subset of the papers summarized so far: https://laion.inference.net/embeddings I typed in "chronic fatigue" and clicked on one at random out of 8 results, and it happened to be authored by @DMissa. I don't see a way to share the link to the summary directly, but...

"Project OSSAS: Custom LLMs to process 100 Million Research Papers" November 11, 2025 "Today, we’re introducing Project OSSAS in collaboration with LAION and Wynd Labs. Project OSSAS is a large-scale open-science initiative to make the world’s scientific knowledge accessible through structured...

Effectiveness and safety of exercise therapy in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): A meta-analysis Zhenya Wei, Heying Wu, Chong Cui, Zixu Wang, Huazhong Xiong, Fujia Song, Jixiang Ren [Line breaks added] Purpose To promote the development of new...

As far as I can tell, they didn't actually cite the 35 m minimum clinically important difference in the present paper. That was a quote from the preprint: Resistance Exercise Therapy for Long COVID: a Randomized, Controlled Trial, 2025, Research Square But they removed that mention of the...

Someone added a comment to the paper (scroll to the bottom): Misleading interpretation of the null results? First paragraph:

Reminder that sharing the full text of the paper on this thread would be breaking the copyright rule, and would end up being removed. Fair use allows sharing brief excerpts for commentary.

Fig. 1: Forest plots for significantly reduced tCho [total choline] in anxiety disorders.

Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a 1H-magnetic resonance spectroscopy meta-analysis Maddock, Richard J.; Smucny, Jason [Line breaks added] Background Anxiety disorders (AnxDs) are highly prevalent and often untreated or unresponsive to...

November 14th, two days from now. Morgane Bomsel, who last year presented some striking differences in megakaryocyte and platelet viral persistence, is presenting again.

I think it's the same data (or at least part of the data is the same), just split by sex, which would explain why the top upregulated genes are almost identical. Very similar cohort numbers, and identical age summaries: Upregulation of olfactory receptors and neuronal-associated genes...

Noting that it was 0-65%.

My impression was that we don't really have good total heritability data. Snippet from 2020 paper from Dibble, Ponting, and McGrath: Genetic risk factors of ME/CFS: a critical review, 2020, Human Molecular Genetics So only two of these were not inconclusive. One of these (UK Biobank, 8%)...

Responding to this from another thread. Relevant part of DecodeME paper: So my understanding is that SNP-based heritability, as reported above, only captures the genetic influence from what was measured in the study: common variants. That means it misses any genetic influence of rare...