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Sure. A questionnaire is absolutely not fool proof and shouldn't be used as a sole determination of donor quality or safety.

True. That is in regards to testing. We can and should determine donor quality through other means, such as a detailed questionnaire. True that adverse events are under reported, but so far the evidence says that FMT is safe if the donor is healthy. The issue comes in with finding someone in...

The current evidence says FMT from high quality donors is safe. So classifying it as a "huge risk" is not evidence-based.

I took a few days break to allow for people to review the relevant information. In science we do not make up our minds. We review the currently available information to try and deduce what the strongest supported position is. When contrary evidence comes along it is vital to be able to switch...

There are many researchers and doctors who will not agree that case reports and citizen science have no value/use. Especially when they are accompanied by a large amount of supporting citations/evidence. There are not multiple documents. There is A document. The rest of the links are scientific...

I'm not in disagreement, just a little confused how these factual statements relate to what was quoted. Getting this large-scale RCT done is exactly what this thread is about. So how do we get it? The problem is that my statements are based on a large amount of supporting evidence, whereas...

Yes, some people believe this, but it's not necessarily the case. Tribal health varies significantly from one tribe to another. They also might be carrying various pathogens. The discussion section of this 2014 review paper "Rural and urban microbiota - To be or not to be?" provides excellent...

I have no idea how you could read what I've written and linked here and then imply that I'm not making an effort. Additionally, I have no idea what your idea of an optimal communication method is. I think the wording you chose is flawed/misleading. It's not simply a "premise" but a fairly well...

All the current evidence says they are not. Beyond the info I shared in the OP, here are more: https://archive.fo/tk0wM Mar 2019 study showing Openbiome donors are causing IBS in 30% of patients: https://archive.fo/eIm25 - nowhere in Openbiome's public safety reports is this mentioned. The...

FMT is only effective if the donor is in perfect health, with an unperturbed, disease-resistant, curative gut microbiome. Most people involved in the gut microbiome & FMT do not seem to understand this notion. They do not seem to have a good understanding of human health and the gut microbiome's...

You can see their donor criteria in the clinicaltrials.gov post and in the final results of the study. Beyond that there is lot of other info and analysis in those links I shared. Including this analysis of Openbiome stool bank: https://archive.fo/JmcMV

I've been following the microbiome literature daily for 4+ years while cataloging it all into this wiki: https://old.reddit.com/r/HumanMicrobiome/wiki/ There is tremendous support for FMT being close to a panacea with the major caveat being that the donor is in perfect health, with an...

These tests have extremely limited value due to current extreme technical & knowledge limitations: https://old.reddit.com/r/HumanMicrobiome/wiki/index#wiki_testing.3A I would not advise anyone to spend money on these tests. Anything you would do after these tests are things you should have...

I've been following the microbiome research daily for 4+ years, have done DIY FMTs with 9 different donors, and catalogue the microbiome/FMT research/info in this wiki: https://old.reddit.com/r/HumanMicrobiome/wiki/ I think FMT is a likely cure but the current limitation is the fact that every...

This should not be in "unrelated to ME/CFS". This may just be the crux of the issue. Mitochondria evolved from microbes, so it makes sense that they would perform a function like this. Since the mitochondria are the main site of energy production it's plausible that chronic infection could...