autoimmune diseases

Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases Abstract Common genetic variants are associated with risk of lung and autoimmune diseases. However, we have a limited understanding of the pathological effects of these disease variants, specifically in...

Teclistamab for treatment-refractory autoimmune diseases: a multicentre case series ABSTRACT Objectives This study aimed to evaluate the safety and efficacy of teclistamab, a T cell–redirecting bispecific antibody targeting B-cell maturation antigen, in a case series of severe autoimmune...

‘It’s all gone’: CAR-T therapy forces autoimmune diseases into remission https://www.nature.com/articles/d41586-023-03968-6 Engineered immune cells have given 15 people with once-debilitating autoimmune disorders a new lease on life, free from fresh symptoms or treatments. The results raise...

Summary Background Case reports suggest that SARS-CoV-2 infection could lead to immune dysregulation and trigger autoimmunity while COVID-19 vaccination is effective against severe COVID-19 outcomes. We aim to examine the association between COVID-19 and development of autoimmune diseases...

Preprint Incident autoimmune diseases in association with a SARS-CoV-2 infection: A matched cohort study Falko Tesch, Franz Ehm, Annika Vivirito, Danny Wende, Manuel Batram, Friedrich Loser, Simone Menzer, Josephine Jacob, Martin Roessler, Martin Seifert, Barbara Kind, Christina König, Claudia...