baricitinib

  1. forestglip

    Open USA: Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms [LC] (REVERSE-LC)

    REVERSE LC is a study to see if an FDA-approved drug called Baricitinib (ber-uh-sit-uh-nib), which is already used to treat COVID, can help improve thinking and memory problems and reduce fatigue for people who have Long COVID. Who Can Participate? Adults 18 and older who have had thinking and...
  2. pooriepoor91

    Potential Mechanism of Fatigue Induction and Its Management by JAK Inhibitors in Inflammatory Rheumatic Diseases 2024, Anna Felis-Giemza et al

    Open Access: Full article: Potential Mechanism of Fatigue Induction and Its Management by JAK Inhibitors in Inflammatory Rheumatic Diseases (tandfonline.com) Abstract It is well known that fatigue is a highly disabling symptom commonly observed in inflammatory rheumatic diseases (IRDs)...
  3. E

    Protocol REVERSE-Long COVID-19 With Baricitinib Study (REVERSE-LC)

    REVERSE-Long COVID-19 With Baricitinib Study (REVERSE-LC) The largest study on Long-Covid initiated by Wes Ely is starting in the upcoming months. In this large (n=550) Randomized, placebo-controlled, double-blind, parallel-design superiority design Phase 3 trial for Long-Covid 4 mg of...
  4. SNT Gatchaman

    Review The JAK/STAT signaling pathway: from bench to clinic, 2021, Hu et al.

    The JAK/STAT signaling pathway: from bench to clinic Hu, Xiaoyi; li, Jing; Fu, Maorong; Zhao, Xia; Wang, Wei The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular...
  5. Mij

    Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19, 2023, Harish Narasimhan et al

    Abstract The long-term health effects of SARS-CoV-2, termed Post-Acute Sequelae of COVID-19 (PASC), are quickly evolving into a major public health concern, but the underlying cellular and molecular etiology remain poorly defined. There is growing evidence that PASC is linked to abnormal immune...
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    • anakinra baricitinib cd8 il-1b long covid t cells
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    • Forum: Long Covid research
  6. J

    Fatigatio meeting Sept 9–livestream from Germany

    https://www.fatigatio.de/aktuelles/detail/me-cfs-und-post-covid-internationale-fachtagung-des-fatigatio-ev-setzt-impulse-fuer-versorgung-forschung-und-aufklaerung
  7. J

    Baricitinib reverses HIV-associated neurocognitive disorders in a SCID mouse model and reservoir seeding in vitro, 2019, Govegnano et al.

    https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1565-6 https://en.wikipedia.org/wiki/Baricitinib
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