bile acid

  1. SNT Gatchaman

    Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling, 2025, Yang et al.

    Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling Yuanheng Yang; Cong Hao; Tingying Jiao; Zidan Yang; Hui Li; Yuqing Zhang; Weiya Zhang; Michael Doherty; Chuying Sun; Tuo Yang; Jiatian Li; Jing Wu; Mengjiao Zhang; Yilun Wang; Dongxing Xie; Tingjian...
  2. pooriepoor91

    Preprint BioMapAI: Artificial Intelligence Multi-Omics Framework Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, 2024, Xiong et al.

    https://www.biorxiv.org/content/10.1101/2024.06.24.600378v1 BioMapAI: Artificial Intelligence Multi-Omics Framework Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome Ruoyun Xiong, Elizabeth Fleming, Ryan Caldwell, Suzanne D. Vernon, Lina Kozhaya, Courtney Gunter, Lucinda...
    • pooriepoor91
    • Thread
    • artificial intelligence bile acid biomapai gamma-delta t cells interferon interferon gamma lipids mait cells multi-omics
    • Replies: 16
    • Forum: ME/CFS research
  3. Andy

    Peroxisomal Regulation of Energy Homeostasis: Effect on Obesity and Related Metabolic Disorders, 2022, Kleiboeker and Lodhi

    Abstract Background Peroxisomes are single membrane-bound organelles named for their role in hydrogen peroxide production and catabolism. However, their cellular functions extend well beyond reactive oxygen species (ROS) metabolism and include fatty acid oxidation of unique substrates that...
  4. Andy

    Altered serum bile acid profile in fibromyalgia is associated with specific gut microbiome changes and symptom severity, 2022, Minerbi et al

    Abstract Alterations in the composition and function of the gut microbiome in women with fibromyalgia have recently been demonstrated, including changes in the relative abundance of certain bile acid metabolizing bacteria. Bile acids can affect multiple physiological processes, including...
  5. Andy

    Co-occurrence of gut microbiota dysbiosis & bile acid metabolism alteration is associated with psychological disorders in Crohn's disease, 2021, Feng

    Abstract This study aims to elucidate the relationships between gut microbiota, bile acid metabolism, and psychological comorbidity in Crohn's disease (CD). We profiled the fecal microbiota composition and quantified the bile acid pool of 39 CD patients and 14 healthy controls using 16S rRNA...
  6. Andy

    Multi-‘omics of gut microbiome-host interactions in short- and long-term myalgic encephalomyelitis/chronic fatigue syndrome patients, 2023, Xiong

    Study now printed, see https://www.s4me.info/threads/preprint-multi-omics-of-host-microbiome-interactions-in-short-and-long-term-myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-2021-xiong.23022/#post-459931 for abstract and link Preprint: Multi-omics of host-microbiome interactions in...
    • Andy
    • Thread
    • 2021 bile acid butyrate dysbiosis gut microbiome jackson labs me/cfs microbiome paper sphingomyelin
    • Replies: 23
    • Forum: ME/CFS research
  7. Andy

    Microbiome-encoded bile acid metabolism modulates colonic transit times, 2021, Li et al

    In mice. Highlights Gut microbiome-generated bile acids regulate colonic transit via TGR5. Lithocholic acid had the largest colonic pro-motility effect. Bile acids exert sex-biased effects on gut transit times. Enteric nervous system transcriptional responses are regional and...
  8. M

    Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder (2021) Naviaux

    This is the latest work of Dr Naviaux and colleagues on cell-danger response, on mice. Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder Abstract Since 2012, studies in mice, rats, and humans have suggested...
    • Milo
    • Thread
    • autism bile acid cell danger response ceramide glutathione naviaux sphingolipids sphingomyelin
    • Replies: 0
    • Forum: Other health news and research
  9. Andy

    Prevalence of biliary acid malabsorption in patients with chronic diarrhoea of functional characteristics: a prospective study, Flores et al, 2021

    Open access, https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-021-01637-4
  10. Andy

    Bile Acid Signaling in Neurodegenerative and Neurological Disorders, 2020, Grant and DeMorrow

    Open access, https://www.mdpi.com/1422-0067/21/17/5982/htm
  11. Andy

    A metabolic pathway for bile acid dehydroxylation by the gut microbiome, 2020, Almo et al

    Paywall, https://www.nature.com/articles/s41586-020-2396-4 Sci hub, https://sci-hub.tw/10.1038/s41586-020-2396-4
  12. Andy

    Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders, 2020, Fiorucci et al

    Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1471489220300175 Sci hub, https://sci-hub.tw/10.1016/j.coph.2020.04.008
  13. Andy

    Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells, 2020, Campbell et al

    Paywall, https://www.nature.com/articles/s41586-020-2193-0 Sci hub, https://sci-hub.tw/10.1038/s41586-020-2193-0
  14. Andy

    Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation, 2020, Bhargarva et al

    Open access, https://www.jci.org/articles/view/129401
  15. Andy

    Global chemical effects of the microbiome include new bile-acid conjugations, 2020, Quinn et al

    Paywall, https://www.nature.com/articles/s41586-020-2047-9 Shared open access PDF...
  16. Andy

    T cell immunomodulation by bile acid metabolites, 2020, Giovannini et al

    A short review/opinion piece. Paywall, https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.14223 Sci hub, https://sci-hub.se/10.1111/all.14223 @mariovitali , another one that will probably interest you. :)
  17. Sly Saint

    Comprehensive Circulatory Metabolomics in ME/CFS Reveals Disrupted Metabolism of Acyl Lipids and Steroids: Levine,Hanson et al 2020

    Article. PDF Received: 20 December 2019; Accepted: 12 January 2020; Published: 14 January 2020...
    • Sly Saint
    • Thread
    • 2020 acyl lipids bile acid circulation levine maureen hanson me/cfs metabolism metabolomics paper sphingolipids steroids susan levine
    • Replies: 40
    • Forum: ME/CFS research
  18. Andy

    Modulation of bile acid profile by gut microbiota in chronic hepatitis B, 2020, Wang et al

    Open access, https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.14951
  19. mariovitali

    Traumatic Brain Injury, Bile Acids and Blood Brain Barrier

    cc @Perrier I had a discussion with Jen Brea on Twitter regarding Traumatic Brain Injury (TBI) and ME. TBI was something i never looked at but i do recall that there are cases of patients that got ME after car accidents. I performed an analysis for TBI to summarise all available information...
  20. Andy

    ..Loss of [GGPDS] Alleviates Acute Obstructive Cholestatic Liver Injury by Regulating Hepatic Bile Acid Metabolism, 2020, Jia et al

    Full title: Conditional Loss of Geranylgeranyl Diphosphate Synthase Alleviates Acute Obstructive Cholestatic Liver Injury by Regulating Hepatic Bile Acid Metabolism In mice. Paywall, https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/febs.15204 Sci hub, https://sci-hub.se/10.1111/febs.15204...
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