C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain
INTRODUCTION
Synaptic elimination is a fundamental process that can engage microglia and the classical complement cascade, yet the mechanisms that specify which synapses are targeted by complement component 1q...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583111/
Abstract
Complement activation resulting in significant increases of C4a split product may be a marker of postexertional malaise in individuals with chronic fatigue syndrome (CFS). This study focused on identification of the transcriptional...
Abstract
Background: Routine blood analytics are systematically used in the clinic to diagnose disease or confirm individuals’ healthy status. For myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a disease relying exclusively on clinical symptoms for its diagnosis, blood analytics...
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