Abstract
Life on Earth has evolved in a form suitable for the gravitational force. Although the pivotal role of gravity in gene expression has been suggested, the molecular details remain unclear. Here, we show that mitochondria utilize gravity to activate protein synthesis within the organelle...
HSF2 is required to maintain cell-cell adhesion
HSF2 deficiency leads to downregulation of cadherin superfamily genes
Impaired cell-cell adhesion sensitizes cells to prolonged proteotoxic stress
Cadherin-mediated cell-cell adhesion is a survival determinant upon proteotoxicity...
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