chemotherapy

In mice, psilocybin given before chemotherapy prevents peripheral neuropathy by acting on the TrkB-Akt-PAK5-MAP2-KIF5B pathway, which is involved in the transport of mitochondria along neuron axons. Sensory neurons have very long axons. Mitochondria are exported from the cell body to the axon...

Lysophospholipid–TRPV1 interactions in chemotherapy-induced neuropathy Chemotherapy-induced peripheral neuropathy (CIPN) is a common and dose-limiting side effect of first-line chemotherapeutics such as paclitaxel, for which effective treatments are currently unavailable. We found that plasma...

There is limited available information on patterns of utilization and efficacy of alternative medicine (AM) for patients with cancer. We identified 281 patients with nonmetastatic breast, prostate, lung, or colorectal cancer who chose AM, administered as sole anticancer treatment among patients...