dementia

  1. Sly Saint

    NICE 2024: Dementia: What else could it be? [Differential diagnosis for cognitive issues, ME not included.]

    This CKS, NICE document relating to Differential diagnosis entitled Dementia; What else could it be? raises several alternative diagnoses but no mention of ME/CFS. Differential diagnosis | Diagnosis | Dementia | CKS | NICE Particularly as we get older, any cognitive issues, (classic for ME...
  2. forestglip

    Trial Report Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: [...], 2025, He et al

    Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial Jiang He, Chuansheng Zhao, Shanshan Zhong, Nanxiang Ouyang, Guozhe Sun, Lixia Qiao, Ruihai Yang, Chunxia Zhao, Huayan Liu, Weiyu Teng, Xu Liu...
  3. forestglip

    Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study, 2024, Yuxia Li et al

    Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study Yuxia Li, Luyao Wang, Jiayi Zhong, Huanyu Xu, Ying Han, Chuantao Zuo, Jiehui Jiang Background: Subjective cognitive decline (SCD) has been recognized as a potential risk stage for...
  4. forestglip

    The recombinant shingles vaccine is associated with lower risk of dementia, 2024, Dercon et al

    The recombinant shingles vaccine is associated with lower risk of dementia Quentin Dercon, John A. Todd, John A. Todd, Paul J. Harrison Published: 25 July 2024 Abstract There is emerging evidence that the live herpes zoster (shingles) vaccine might protect against dementia. However, the...
  5. forestglip

    A Possible Reversible Cause of Cognitive Impairment: Undiagnosed Cirrhosis and Potential Hepatic Encephalopathy in [...] Dementia, 2024, Silvey et al

    A Possible Reversible Cause of Cognitive Impairment: Undiagnosed Cirrhosis and Potential Hepatic Encephalopathy in Patients with Dementia Scott Silvey, Richard Sterling, Evan French, Michael Godschalk, Angela Gentili, Nilang Patel, Jasmohan Bajaj Background Dementia and hepatic encephalopathy...
  6. forestglip

    Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies, 2024, Gibbons et al

    Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies Authors Abstract Importance Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD], dementia with Lewy bodies [DLB], multiple system...
  7. E

    Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons , 2023, Di Primo et al

    Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons Abstract COVID-19 has represented an issue for global health since its outbreak in March 2020. It is now evident that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
  8. SNT Gatchaman

    Neurological and psychiatric risk trajectories after SARS-CoV-2 infection (2022, Taquet et al)

    Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients Maxime Taquet, PhD; Rebecca Sillett, BA; Lena Zhu, BS; Jacob Mendel, MMath; Isabella Camplisson, BS; Quentin Dercon, MSc; Paul J Harrison...
  9. Mij

    An Association of Pathogens and Biofilms with Alzheimer’s Disease, 2021

    Abstract As one of the leading causes of dementia, Alzheimer’s disease (AD) is a condition in which individuals experience progressive cognitive decline. Although it is known that beta-amyloid (Aβ) deposits and neurofibrillary tangles (NFT) of tau fibrils are hallmark characteristics of AD, the...
  10. Colin

    Uncovering the prevalence and neural substrates of anhedonia in frontotemporal dementia (2021) Shaw et al

    Abstract Much of human behaviour is motivated by the drive to experience pleasure. The capacity to envisage pleasurable outcomes and to engage in goal-directed behaviour to secure these outcomes depends upon the integrity of frontostriatal circuits in the brain. Anhedonia refers to the...
  11. Trish

    'The dementia that can be cured' - Guardian article about autoimmune neurological diseases, 2020

    https://www.theguardian.com/science/2020/oct/25/the-dementia-that-can-be-cured The dementia that can be cured Treatments mentioned include steroids, rituximab and plasma exchange.
  12. Patient4Life

    Lewy Body Disease and Prilosec OTC

    Prilosec Why is this statement significant for patients with Lewy Body Disease? (LBD) Because this OTC signals the brain to turn off the proton pump in the stomach. Apparently for LBD patients, changing brain signals pushes the patients into the disease. My sister related this information to...
  13. Andy

    Drugs that quell brain inflammation reverse dementia

    https://neurosciencenews.com/inflammation-drugs-dementia-15285/
  14. wastwater

    Alzheimer’s Society blog - a new type of dementia called LATE, 2019

    https://www.alzheimers.org.uk/blog/late-new-type-dementia New type of dementia discovered
  15. adambeyoncelowe

    Do Alzheimer's and Lewy body disease have discrete pathological signatures of gait?

    Thought this was relevant since @Jonathan Edwards has mentioned gait as a possible diagnostic tool in ME. Link: https://www.alzheimersanddementia.com/article/S1552-5260(19)35120-9/fulltext
  16. obeat

    Machine learning and dementia subtypes.

    https://m.medicalxpress.com/news/2018-10-machine-uncovers-dementia-subtypes-implication.html Just thought this was interesting in relation to how subtypes are being found in other illness.
  17. NelliePledge

    Dementia and Parkinson’s linked to DNA changes when embryo is developing

    https://www.sciencedaily.com/releases/2018/10/181015084602.htm
  18. Alvin

    When ICU Delirium Leads To Symptoms Of Dementia After Discharge

    https://www.npr.org/sections/health-shots/2018/10/10/654445929/when-icu-delirium-leads-to-symptoms-of-dementia-after-discharge
  19. Rick Sanchez

    Rigorous exercise does not halt dementia

    Rigorous exercise does not halt dementia decline, study concludes Keeping active helps prevent the onset of dementia, but once the disease has taken hold, working out more does nothing to slow its progress Guardian article available @...
  20. Andy

    Medscape: More Evidence Anticholinergic Meds Boost Dementia Risk

    https://www.medscape.com/viewarticle/896005
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