NIH study by Nicholas Madian (who administered the EEfRT in the intramural study) and Eric Wasserman
Study Overview
Brief Summary
Background:
The way the brain processes rewards and punishments may play a role in some disorders of the nervous system. People with chronic overlapping pain...
Repeated Handgrip Strength Variability in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Separating Disease-Related Fatigability from Force Gradation
BACKGROUND
Force production reflects neuromuscular capacity, central regulation, and sensory feedback, making performance-based testing...
Cholinergic modulation of dopamine release drives effortful behaviour
Effort is costly: given a choice, we tend to avoid it1. However, in many cases, effort adds value to the ensuing rewards2. From ants3 to humans4, individuals prefer rewards that had been harder to achieve. This...
Andrew Kirvin-Quamme, Karen D. Kirke, Oscar Junge, Jonathan C. W. Edwards, Kevin J. Holmes
Introduction
In a recent, high-profile study of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS), Walitt et al. (2024) assessed the performance of patients and healthy...
Neuroimaging markers of cognitive fatigue in individuals with post-acute sequelae of SARS-CoV-2 infection
Niemczak; Ford; Roth; Leigh; Parsonnet; Martin; Soule; Haron; Buckey Jr.; Wylie
Persistent cognitive fatigue (CF) is the most reported symptom in Post-Acute Sequelae of SARS-CoV-2 Infection...
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