Estrogen-Related Receptor α: A Key Transcription Factor in the Regulation of Energy Metabolism at an Organismic Level and a Target of the ABA/LANCL Hormone Receptor System
Spinelli, Sonia; Bruschi, Maurizio; Passalacqua, Mario; Guida, Lucrezia; Magnone, Mirko; Sturla, Laura; Zocchi, Elena
The...
A novel estrogen receptor 1: sphingomyelin phosphodiesterase acid-like 3B pathway mediates rituximab response in myositis patients
Parkes, Joanna E; Boehler, Jessica F; Li, Ning; Kendra, Ryan M; O’Hanlon, Terrance P; Hoffman, Eric P; Peterson, Jennifer M; Miller, Frederick W; Rider, Lisa G...
Abstract.
Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that Esrrg controls regulatory T cells (Treg) through mitochondria homeostasis. Esrrg deficiency impaired the maintenance and function of Treg cells...
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