glutamate

New insights into how glutamate opens brain cell signaling channels eta: Journal reference: Mondal, A. K., et al. (2025). Glutamate gating of AMPA-subtype iGluRs at physiological temperatures. Nature. doi.org/10.1038/s41586-025-08770-0.

Asymmetrical glymphatic dysfunction in patients with long Covid associated neurocognitive impairment- correlation with BBB disruption Chaganti, Joga R.; Talekar, Tanush K.; Brew, Bruce James BACKGROUND AND PURPOSE The glymphatic system, a waste clearance pathway, has been implicated in several...

Neurometabolic network NMetNet for functional neurological disorder in children and adolescents Lan; Foster; Charney; Grinsven; Breedlove; Kozlowska; Lin OBJECTIVES Functional neurological disorder (FND) in children and adolescents is a biopsychosocially-complex condition characterized by a...

Delayed-Onset Muscle Soreness Begins with a Transient Neural Switch Sonkodi, Balázs Unaccustomed and/or strenuous eccentric contractions are known to cause delayed-onset muscle soreness. In spite of this fact, their exact cause and mechanism have been unknown for more than 120 years. The...

Longitudinal multi-omics analysis of convalescent individuals with respiratory sequelae 6–36 months after COVID-19 Yang, Huqin; Guan, Lujia; Xue, Yi; Li, Xuyan; Gao, Leyi; Zhang, Zhijin; Zhang, Haifan; Ma, Haomiao; Liu, Fengjiao; Huang, Xuan; Tong, Zhaohui; Li, Jieqiong Approximately 10–30% of...

Epigenetic patterns, accelerated biological aging, and enhanced epigenetic: drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study, 2024, Calzari Luciano, Dragani Davide Fernando et al Abstract Background The epigenetic status of patients 6-month...

Open access https://journals.sagepub.com/doi/10.1177/0271678X241270528 Research article First published online August 7, 2024 Absence of BOLD adaptation in chronic fatigue syndrome revealed by task functional MRI Laura Schönberg, Abdalla Z Mohamed, Qiang Yu, Richard A Kwiatek, Peter Del Fante...

Blood brain barrier disruption and glutamatergic excitotoxicity in post-acute sequelae of SARS COV-2 infection cognitive impairment: potential biomarkers and a window into pathogenesis Chaganti, Joga; Poudel, Govinda; Cysique, Lucette Adeline; Dore, Gregory J.; Kelleher, Anthony; Matthews, Gael...

https://www.sciencedirect.com/science/article/pii/S000293432400216X Imbalanced Brain Neurochemicals in long COVID and ME/CFS: A Preliminary Study using MRI Kiran Thapaliya, PhD 1*, Sonya Marshall-Gradisnik, PhD 1 , Natalie Eaton-Fitch, PhD 1 , Zeinab Eftekhari BSc (Honours)2 ,Maira Inderyas...

Polysomnography has shown that I have Periodic Limb Movement Disorder (PLMD). I also tick all boxes for RLS (and never been diagnosed with fibromyalgia). I can't describe how happy I was to see, written in black and white, numerically quantified, accompanied by "obviously [patient] has PLMD that...

Metabolic Fingerprinting for the Diagnosis of Clinically Similar Long COVID and Fibromyalgia Using a Portable FT-MIR Spectroscopic Combined with Chemometrics Hackshaw, Kevin V.; Yao, Siyu; Bao, Haona; de Lamo Castellvi, Silvia; Aziz, Rija; Nuguri, Shreya Madhav; Yu, Lianbo; Osuna-Diaz, Michelle...

Brain fog in long COVID: A glutamatergic hypothesis with astrocyte dysfunction accounting for brain PET glucose hypometabolism Abstract Brain [18F]FDG-PET scans have revealed a glucose hypometabolic pattern in patients with long COVID. This hypometabolism might reflect primary astrocyte...

Differential effects of SARS-CoV-2 variants on central nervous system cells and blood–brain barrier functions Background Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus affects the...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409949/ Gambierdiscus species are the producers of the marine toxins ciguatoxins and maitotoxins which cause worldwide human intoxications recognized as Ciguatera Fish Poisoning. A deep chemical investigation of a cultured strain of G. belizeanus...

Full title: Multimodal MRI of myalgic encephalomyelitis/chronic fatigue syndrome: A cross-sectional neuroimaging study toward its neuropathophysiology and diagnosis Introduction: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is a debilitating illness affecting up to 24 million...

Highlights Cognitive fatigue is explored with magnetic resonance spectroscopy during a workday Hard cognitive work leads to glutamate accumulation in the lateral prefrontal cortex The need for glutamate regulation reduces the control exerted over decision-making Reduced control favors the...

Open access, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0244116

Objectives The objective of this research was to investigate a novel low glutamate dietary intervention for Gulf War Illness (GWI), a chronic multi-symptom disorder that includes cognitive dysfunction. Methods Forty GW veterans with GWI were recruited from across the US. As part of a larger...

Paywall, https://www.sciencedirect.com/science/article/abs/pii/S0161813X20300954 Not available via Sci hub at time of posting.

"Mediation of the acute stress response by the skeleton," Cell Metabolism (2019). DOI: 10.1016/j.cmet.2019.08.012 , https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30441-3 Mediation of the Acute Stress Response by the Skeleton Author links open overlay panelJulian...