gtex

  1. ME/CFS Science Blog

    Overview of RNA datasets for tissue and cell type enrichment analysis

    I thought it would be useful to make an overview of RNA datasets that we can match to the DecodeME DNA results. This could give us clues to which tissues or cell types are potentially involved in ME/CFS. I've made an overview of datasets below and plan to update it as we find new ones. The Chan...
  2. ME/CFS Science Blog

    Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types, 2018, Finucane et al.

    Abstract We introduce an approach to identify disease-relevant tissues and cell types by analyzing gene expression data together with genome-wide association study (GWAS) summary statistics. Our approach uses stratified linkage disequilibrium (LD) score regression to test whether disease...
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