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  1. hotblack

    New overlapping and disease-specific genetic risk factors for rheumatoid arthritis & ankylosing spondylitis, 2026, Cabrera-Serrano et al

    Identification of new overlapping and disease-specific genetic risk factors for rheumatoid arthritis and radiographic axial spondyloarthritis: a meta-analysis of three large European populations and functional characterization Abstract This study conducted a meta-analysis across three large...
  2. SNT Gatchaman

    Dysfunction of Primary Cilium in Huntington’s Disease: How Mutant Huntingtin Disrupts This Cellular Signaling Hub, 2026, Churkina et al.

    Dysfunction of Primary Cilium in Huntington’s Disease: How Mutant Huntingtin Disrupts This Cellular Signaling Hub Churkina, Aleksandra S; Shakhov, Anton S; Alieva, Irina B Primary cilia are solitary, antenna-like organelles that project from the surface of most vertebrate cells. They consist of...
  3. Hutan

    Genetics: Chromosome 4, HTT

    From a discussion on the Eccentric Medium Spiny Neurons thread: DecodeME identified HTT as of interest.
  4. Hutan

    Genetics: Chromosome 1 RABGAP1L, GPR52, SERPINC1

    From DecodeME Candidate Genes: RABGAP1L (Tier 1) • Protein: RAB GTPase-activating protein 1-like, also known as TBC1D18. UniProt. GeneCards. The allele that increases the risk of ME/CFS is associated with decreasing RABGAP1L gene expression. • Molecular function: GTP-hydrolysis activating...
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