il-17

  1. SNT Gatchaman

    Preprint Longitudinal immune profiling of Long COVID phenotypes reveals a shared persistent IL-17F-centered immune signature, 2026, Kumar-Singh et al.

    Longitudinal immune profiling of Long COVID phenotypes reveals a shared persistent IL-17F-centered immune signature The longitudinal immunological mechanisms driving the heterogeneous clinical phenotypes of Long COVID (LC) remain poorly understood. Here, we quantified 54 circulating immune...
  2. forestglip

    Small extracellular vesicles proteome reveals persistent inflammatory and coagulopathic dysregulation in long-COVID, 2026, Chandran et al

    Small extracellular vesicles proteome reveals persistent inflammatory and coagulopathic dysregulation in long-COVID Background Post-acute sequelae of SARS-CoV-2 (PASC) or Long-COVID affects millions and remains mechanistically undefined due to its heterogeneous clinical presentation...
  3. SNT Gatchaman

    Preprint Monocyte Oxidative Stress Underlies Persistent Immune Activation in Long-COVID Postural Orthostatic Tachycardia Syndrome, 2026, Abd-Eldayem et al.

    Monocyte Oxidative Stress Underlies Persistent Immune Activation in Long-COVID Postural Orthostatic Tachycardia Syndrome BACKGROUND Long COVID postural orthostatic tachycardia syndrome (LCPOTS) is characterized by persistent orthostatic tachycardia and multiple constitutional symptoms, many of...
  4. SNT Gatchaman

    Long-term immune and epigenetic dysregulation following COVID-19, 2026, Sidiropoulou et al.

    Long-term immune and epigenetic dysregulation following COVID-19 Post-Acute COVID-19 syndrome (PACS) is heterogeneous in phenotype and functional state. This prospective, observational study studied adults six months after acute COVID-19. We defined clinical phenotypes and profiled plasma...
  5. T

    Temporal dynamics of the plasma proteomic landscape reveals maladaptation in ME/CFS following exertion, 2025, Germain et al.

    Highlights • Plasma profiling of 7,288 proteins during post-exertional malaise in ME/CFS. • ME/CFS participants show sustained immune, metabolic, and neuromuscular dysregulation during post-exercise recovery. • Exertion disrupts T and B cell signaling, IL-17 pathways, and mitochondrial...
  6. SNT Gatchaman

    Interferon-Linked Lipid and Bile Acid Imbalance Uncovered in Ankylosing Spondylitis in a Sibling-Controlled Multi-Omics Study, 2025, Wang et al.

    Interferon-Linked Lipid and Bile Acid Imbalance Uncovered in Ankylosing Spondylitis in a Sibling-Controlled Multi-Omics Study Ankylosing spondylitis (AS) displays wide inter-patient variability that is not accounted for by HLA-B27 alone, suggesting that additional immune and metabolic...
  7. SNT Gatchaman

    Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation, 2025, White et al.

    Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation White, Zachary; Cabrera, Ivan; Mei, Linghan; Clevenger, Margarette; Ochoa-Raya, Andrea; Kapustka, Isabel; Dominguez, Joseph R.; Zhou, Jinyan; Koster, Kevin P.; Anwar, Shehata; Wang, Qianxun; Ng, Charles; Sagoshi...
  8. SNT Gatchaman

    Longitudinal lipoprotein and inflammatory mediators analysis uncover persisting inflammation and hyperlipidemia…, 2025, Bae+

    Longitudinal lipoprotein and inflammatory mediators analysis uncover persisting inflammation and hyperlipidemia following SARS-CoV-2 infection in long COVID-19 Bae, Gyuntae; Yang, Zhiqi; Bucci, Daniele; Wegner, Claire; Schäfer, Hartmut; Singh, Yogesh; Lonati, Caterina; Trautwein, Christoph...
  9. Dolphin

    Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In [ME/CFS],2025, Lee, Cliff et al

    https://www.medrxiv.org/content/10.1101/2025.01.02.24319359v1 Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Ji-Sook Lee1,3, Eliana Lacerda2, Caroline Kingdon 2, Giada Susannini1, Hazel M Dockrell1...
  10. SNT Gatchaman

    Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure, 2024, Saleem et al.

    Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure Mohammad Saleem; Luul A. Aden; Ashley L. Mutchler; Chitra Basu; Lale A. Ertuglu; Quanhu Sheng; Niki Penner; Anna R. Hemnes; Jennifer H. Park; Jeanne A. Ishimwe; Cheryl L. Laffer; Fernando Elijovich...
  11. Mij

    Cytokine deficiencies in patients with Long-COVID, 2022, Vicente Planelles et al

    Preprint Plasma cytokine levels reveal deficiencies in IL-8 and gamma interferon in Long-COVID, 2022, Elizabeth S C P Williams et al See post #8 for published version Abstract Up to half of individuals who contract SARS-CoV-2 develop symptoms of long-COVID approximately three months after...
  12. Mij

    IL-17 controls central nervous system autoimmunity through the intestinal microbiome, 2021 Tommy Regen et al

    IL-17 controls central nervous system autoimmunity through the intestinal microbiome. https://immunology.sciencemag.org/content/6/56/eaaz6563
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