ldsc

Abstract With few exceptions, the marked advances in knowledge about the genetic basis of schizophrenia have not converged on findings that can be confidently used for precise experimental modeling. By applying knowledge of the cellular taxonomy of the brain from single-cell RNA sequencing, we...

I thought it would be useful to make an overview of RNA datasets that we can match to the DecodeME DNA results. This could give us clues to which tissues or cell types are potentially involved in ME/CFS. I've made an overview of datasets below and plan to update it as we find new ones. The Chan...

Abstract We introduce an approach to identify disease-relevant tissues and cell types by analyzing gene expression data together with genome-wide association study (GWAS) summary statistics. Our approach uses stratified linkage disequilibrium (LD) score regression to test whether disease...