maes

Molecular Mimicry Between Epstein-Barr Virus and Human Herpesvirus-6 Proteins and Central Nervous System Proteins: Implications for T and B Cell Immunogenicity in an In Silico Study. preprint Abstract Background: The Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6) are frequently...

Immune Cell Exhaustion and Apoptotic Markers in Major Depressive Disorder: Effects of in Vitro Cannabidiol Administration. Muanpetch Rachayon, Ketsupar Jirakran, Pimpayao Sodsai, Chawit Tunvirachaisakul, Atapol Sughondhabirom, Yingqian Zhang, Jing Li, Michael Maes Background Immune...

Aug 2023 Michael Maes et al Abstract Background: Major depressive disorder (MDD) is accompanied by activated neuro-immune pathways, increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The most severe MDD phenotype, namely major dysmood disorder (MDMD), is associated with...

a prolific producer of published papers, often citing his own work/papers. How much of it can be trusted? Michael MAES | M.D., Ph.D. Professor | King Chulalongkorn Memorial Hospital, Bangkok | Department of Psychiatry | Research profile (researchgate.net)

Critical COVID-19 disease is accompanied by depletion of plasma tryptophan (TRY) and increases in indoleamine-dioxygenase (IDO)-stimulated production of neuroactive tryptophan catabolites (TRYCATs), including kynurenine (KYN). The TRYCAT pathway has not been studied extensively in association...

Full title: Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study Abstract The immune-inflammatory response during the acute phase of COVID-19, as assessed using...

Title Aberrations in the Cross-Talks Among Redox, Nuclear Factor-κB and Wnt/Catenin Pathway Signaling Underpin Myalgic Encephalomyelitis and Chronic Fatigue Syndrome: A Review and New Hypothesis Based on Results of Network, Enrichment and Annotation Analyses Abstract There is evidence that...

Full title: The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups https://www.preprints.org/manuscript/202101.0623/v1

Preprint https://www.researchgate.net/publication/339886499_Mitochondria_and_Immunity_in_Chronic_Fatigue_Syndrome Free full text...

Full title: Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function: Assessment, Treatment and Classification Implications Paywall, http://www.eurekaselect.com/178870/article Not available via Sci hub at time of posting.

And the title is all I can access at the moment. Paywalled at https://www.tandfonline.com/doi/full/10.1080/14737159.2020.1681976 Not currently available through Scihub.

https://link.springer.com/article/10.1007%2Fs11011-019-0388-6

This version is not peer-reviewed https://www.preprints.org/manuscript/201902.0029/v1...

This is a few years old, but really highlights the similarities between these two illnesses (and thus makes the difference in treatments more stark). Does anybody with any understanding of the specifics here have any comments? What do we think: is ME like MS? Certainly, the early literature...