medium spiny projection neurons

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways Insomnia is the second most prevalent mental disorder, with no sufficient treatment available. Despite substantial heritability, insight into the associated genes and neurobiological...

Alcohol-driven AMPA receptor dysregulation across the lifespan Alcohol use produces persistent alterations in glutamatergic signaling that evolve across the lifespan, with α-amino-3‑hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) emerging as major contributors to these...

Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales—Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2 Abstract The basal ganglia are involved in the motivational and habitual control of motor and...