metabolomics

Children with Post COVID-19 Multisystem Inflammatory Syndrome Display Unique Pathophysiological Metabolic Phenotypes Nathan G. Lawler; Lael M. Yonker; Samantha Lodge; Philipp Nitschke; Maureen M. Leonard; Nicola Gray; Luke Whiley; Reika Masuda; Elaine Holmes; Julien Wist; Alessio Fasano; Jeremy...

Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19 Ronaldo Lira-Junior; Anoop Ambikan; Axel Cederholm; Ssefanit Rezene; Flora Mikaeloff; Sara Svensson Akusjarvi; Ahmet Yalcinkaya; Xi Chen; Maike Sperk...

Abstract: We proposed that cerebrospinal fluid would provide objective evidence for disrupted brain metabolism in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS). The concept of postexertional malaise (PEM) with disabling symptom exacerbation after limited exertion that does not...

Abstract Sleep deprivation enhances risk for serious injury and fatality on the roads and in workplaces. To facilitate future management of these risks through advanced detection, we developed and validated a metabolomic biomarker of sleep deprivation in healthy, young participants, across three...

Proteomic and metabolomic profiling of plasma uncovers immune responses in patients with Long COVID-19 Yulin Wei, Hongyan Gu, Jun Ma, Xiaojuan Mao, Bing Wang, Weiyan Wu, Shimin Yu, Jinyuan Wang, Huan Zhao, yanbin he [Preprint] Abstract Long COVID is an often-debilitating condition with...

Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher & Christopher W. Armstrong Abstract Background Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and...

Fast Targeted Metabolomics for Analyzing Metabolic Diversity of Bacterial Indole Derivatives in ME/CFS Gut Microbiome Huidi Tian; Lei Wang; Elizabeth Aiken; Robert Jervine V. Ortega; Rachel Hardy; Lindsey Placek; Lina Kozhaya; Derya Unutmaz; Julia Oh; Xudong Yao Disruptions in microbial...

Free fulltext: https://e-jespar.com/index.php/jespar/article/view/25 Prediction of myalgic chronic fatigue syndrome disorder with machine learning approach Authors Fatma Hilal Yagin Badicu Georgian Department of Physical Education and Special Motricity, Transilvania University of Brasov...

Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens Neu, Frieder; Nay, Sandra; Schuchardt, Sven; Klawonn, Frank; Skripuletz, Thomas; Suehs, Kurt-Wolfram...

Exploring Metabolic Anomalies in COVID-19 and Post-COVID-19: A Machine Learning Approach with Explainable Artificial Intelligence Juan José Oropeza-Valdez; Cristian Padron-Manrique; Aaron Vazquez-Jimenez; Xavier Soberon-Mainero; Osbaldo Resendis-Antonio The COVID-19 pandemic, caused by...

In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice, 2024, Marcus M. Garcia, et al. https://ehp.niehs.nih.gov/doi/10.1289/EHP13435 https://doi.org/10.1289/EHP13435 PDF (auto-download) Abstract Background: Global plastic...

Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach Sara Martínez; Oihane E. Albóniga; María Rosa López-Huertas; Ana Gradillas; Coral Barbas Despite the recent and increasing knowledge surrounding...

Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets Gerhard Hagn; Samuel M. Meier-Menches; Günter Plessl-Walder; Gaurav Mitra; Thomas Mohr; Karin Preindl; Andreas Schlatter; Doreen Schmidl; Christopher Gerner; Gerhard Garhöfer; Andrea Bileck...

Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight Anurag Sakharkar; Kiven Erique Lukong; Lauren M Sanders; Sylvain V Costes; Jian Yang; Changiz Taghibiglou Space exploration has captured the imagination of humanity for generations. From the first steps on the moon to...

Circulating Metabolome and White Matter Hyperintensities in Women and Men Eeva Sliz; Jean Shin; Shahzad Ahmad; Dylan M. Williams; Stefan Frenzel; Friederike Gauß; Sarah E. Harris; Ann-Kristin Henning; Maria Valdes Hernandez; Yi-Han Hu; Beatriz Jiménez; Muralidharan Sargurupremraj; Carole Sudre...

https://onlinelibrary.wiley.com/doi/10.1111/all.15253 Letter, open access Cork study Serum was obtained from PASC patients (n = 20) at two time points (4–6 months following infection (T1) and 6–9 months following infection (T2)). All patients had been hospitalized for PCR-proven SARS-CoV-2...

Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity and Early Mortality Prediction Lodge, Samantha; Lawler, Nathan G.; Gray, Nicola; Masuda, Reika; Nitschke, Philipp; Whiley, Luke; Bong, Sze-How; Yeap, Bu B.; Dwivedi, Girish; Spraul...

Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL Moon, Jee-Young;Chai, Jin Choul;Yu, Bing;Song, Rebecca J.;Chen, Guo-Chong;Graff, Mariaelisa;Daviglus, Martha L.;Chan, Queenie;Thyagarajan, Bharat;Castaneda, Sheila F.;Grove...

SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution Rafael J. Argüello; Alexis J. Combes; Remy Char; Julien-Paul Gigan; Ania I. Baaziz; Evens Bousiquot; Voahirana Camosseto; Bushra Samad; Jessica Tsui; Peter Yan; Sebastien Boissonneau...

Introduction: Similar to what it has been reported with preceding viral epidemics (such as MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human immunometabolism with long-term consequences. Even with underreporting, an accumulated of almost 650 million people have been...