HSP60 and SARS-CoV-2: Les Liaisons Dangereuses
Simple Summary
This review examines the role of heat shock protein 60 (Hsp60) in COVID-19, highlighting its impact on immune modulation, inflammation, and endothelial dysfunction. Hsp60, a chaperone protein essential for protein folding and...
Post-COVID-19 immune dysregulation and autoimmune sequelae
Abdel-Moneim, Ahmed S.; Al-Balushi, Mohammad S.; Al-Jabri, Ali A.
Highlights
SARS-CoV-2 infection can induce persistent immune dysregulation : hyperinflammation, lymphopenia, and innate–adaptive imbalance.
Molecular mimicry, bystander...
Adenoviral Inciting Antigen and Somatic Hypermutation in VITT
BACKGROUND
Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare prothrombotic complication that occurs after adenoviral vector–based vaccination against coronavirus disease 2019; in rare cases, it can also occur...
Abstract
Multiple sclerosis (MS) occurs when the central nervous system (CNS) is damaged by misguided adaptive immune responses, likely caused by a combination of environmental factors in genetically susceptible individuals. A known prerequisite for disease is Epstein-Barr virus (EBV)...
Open Access
Published: 08 January 2023
Sequence similarity between SARS-CoV-2 nucleocapsid and multiple sclerosis-associated proteins provides insight into viral neuropathogenesis following infection
Camille M. Lake &
Joseph J. Breen
Scientific Reports volume 13, Article number: 389 (2023)...
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