Immunothrombosis in hospitalized COVID-19 patients identified by multiomics profiling and linked to postacute complications
Post-acute sequelae of COVID-19 (PASC) disproportionately affect hospitalized patients and require improved molecular characterization to inform patient management...
De novo COVID-19-associated insulin resistance drives dysregulated neutrophil extracellular trap formation (NETosis) four months after infection
Abstract
Background
Glucose metabolism disorders (GMDs) are established risk factors for severe COVID-19, but increasing evidence indicates that...
Endovascular profiles linked to neutrophil activation in children and young adults with long COVID
Endovascular symptoms are among the most debilitating long COVID symptoms; however, underlying mechanisms are unclear. Children and young adults with long COVID, an understudied population, offer...
NET Biomarkers in COVID-19 and Post-COVID Syndrome: a Comprehensive Analysis
SARS-CoV-2 triggers immune responses, including neutrophil activation and neutrophil extracellular trap (NET) release, contributing to COVID-19 severity. A significant proportion of patients experience persistent or...
Sars-Cov-2 spike protein and plasma from COVID-19 patients induce extracellular traps by myeloid-derived suppressor cells
INTRODUCTION
Polymorphonuclear-myeloid-derived suppressor cells (PMN-MDSC) are elevated in COVID-19 patients, playing a crucial role in suppressing the SARS-CoV-2 specific...
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