Dynamic cerebral autoregulation in people with mild cognitive impairment
Laura K Fitzgibbon-Collins; Michael Borrie; Sue Peters; J Kevin Shoemaker; Jaspreet Bhangu
Altered cerebrovascular hemodynamics and low cerebral perfusion contribute to the development and progression of dementia. Dynamic...
Need for awareness and surveillance of long-term post-COVID neurodegenerative disorders. A position paper from the neuroCOVID‐19 task force of the European Academy of Neurology
Bereczki, Dániel; Dénes, Ádám; Boneschi, Filippo M.; Akhvlediani, Tamar; Cavallieri, Francesco; Fanciulli, Alessandra...
Endogenous self-peptides guard immune privilege of the central nervous system
Kim, Min Woo; Gao, Wenqing; Lichti, Cheryl F.; Gu, Xingxing; Dykstra, Taitea; Cao, Jay; Smirnov, Igor; Boskovic, Pavle; Kleverov, Denis; Salvador, Andrea F. M.; Drieu, Antoine; Kim, Kyungdeok; Blackburn, Susan; Crewe...
Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
Hannah Scheiblich; Frederik Eikens; Lena Wischhof; Sabine Opitz; Kay Jüngling; Csaba Cserép; Susanne V. Schmidt; Jessica Lambertz; Tracy Bellande; Balázs Pósfai; Charlotte Geck; Jasper...
The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics
Pileggi; Parmar; Elkhatib; Stewart; Alecu; Côté; Bennett; Sandhu; Cuperlovic-Culf; Harper
SARS-CoV-2 infection is associated with both acute and post-acute neurological symptoms. Emerging evidence...
Similar to doing an MOT on a car, scientists believe they can run a blood test to check how fast a person's internal organs are ageing, and even predict which ones might soon fail.
The Stanford University team say they can monitor 11 major body parts, including the heart, brain and lungs.
They...
Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death
Background
We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during...
Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis
Asim Cengiz Akbulut; Ryanne A. Arisz; Constance C. F. M. J. Baaten; Gaukhar Baidildinova; Aarazo Barakzie; Rupert Bauersachs; Jur ten Berg; Wout W. A. van den Broek; H. C. de Boer; Amandine...
SARS-CoV-2 Spike amyloid fibrils specifically and selectively accelerates amyloid fibril formation of human prion protein and the amyloid β peptide
Abstract
An increasing number of reports suggest an association between COVID-19 infection and initiation or acceleration of neurodegenerative...
Distinct molecular profiles of skull bone marrow in health and neurological disorders
Zeynep Ilgin Kolabas; Louis B. Kuemmerle; Robert Perneczky; Benjamin Förstera; Selin Ulukaya; Mayar Ali; Saketh Kapoor; Laura M. Bartos; Maren Büttner; Ozum Sehnaz Caliskan; Zhouyi Rong; Hongcheng Mai; Luciano...
Pathophysiology, diagnosis, and management of neuroinflammation in covid-19
Rachel L Brown; Laura Benjamin; Michael P Lunn; Tehmina Bharucha; Michael S Zandi; Chandrashekar Hoskote; Patricia McNamara; Hadi Manji
Although neurological complications of SARS-CoV-2 infection are relatively rare...
The Human Microglia Atlas HuMicA Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative Conditions
Ricardo Martins-Ferreira; Josep Calafell-Segura; Barbara Leal; Javier Rodriguez-Ubreva; Elisabetta Mereu; Paulo Pinho e Costa; Esteban Ballestar...
The impact of viral infections on the brain has been long studied in the context of rabies, herpes simplex, HIV, measles, and a few other viruses that target the organ directly, but little has been known about indirect effects of viral infections. This specific research has been boosted though...
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