neutrophil extracellular traps

Neutrophil extracellular traps and macrophage activation contibute to thrombosis and post-covid syndrome in SARS-CoV-2 infection Serrano-Gonzalo, Irene; Menéndez-Jandula, Bárbara; Franco-García, Esther; Arévalo-Vargas, Isidro; Lahoz-Gil, Calos; Latre, Paz; Roca-Esteve, Sonia; Köhler, Ralf; López...

Exercise intensity and training alter the innate immune cell type and chromosomal origins of circulating cell-free DNA in humans Rodrigues, Kameron B.; Weng, Ziming; Graham, Zachary A.; Lavin, Kaleen; McAdam, Jeremy; Tuggle, S. Craig; Peoples, Brandon; Seay, Regina; Yang, Sufen; Bamman, Marcas...

Neutrophil Elastase, Neuron-Specific Enolase, and S100B Protein as Potential Markers of Long-Term Complications Caused by COVID-19 in Patients with Type 2 Diabetes Mellitus T2DM and Advanced Stage of Diabetic Nephropathy NfT2DM—Observational Studies Rabczyński, Maciej; Chwałek, Sandra...

Association of vascular netosis with COVID-19 severity in asymptomatic and symptomatic patients Suman Kapoor; Lucia Mihalovičová; Ekaterina Pisareva; Brice Pastor; Alexia Mirandola; Benoit Roch; Joe Bryant; Anna Philip Princy; Salem Chouaib; Alain Roger Thierry We examined from a large...

Inflammation-, immunothrombosis,- and autoimmune-feedback loops may lead to persistent neutrophil self-stimulation in long COVID Alain R. Thierry; Dominique Salmon Understanding the pathophysiology of long COVID is one of the most intriguing challenges confronting contemporary medicine. Despite...

Circulating microclots are structurally associated with Neutrophil Extracellular Traps and their amounts are strongly elevated in long COVID patients Etheresia Pretorius¹, Alain THIERRY², Cynthia Sanchez³, Tram Ha⁴, Brice Pastor⁴, Alexia Mirandola³, Ekaterina Pisareva⁵, Corinne Prevostel⁶, Gert...

Blood test that can rapidly identify sepsis being trialled in UK (msn.com)

Understanding COVID-19 progression with longitudinal peripheral blood mononuclear cell proteomics: Changes in the cellular proteome over time Giuseppe Gianini Figueirêdo Leite; Milena Karina Colo Brunialti; Paula M. Peçanha-Pietrobom; Paulo R. Abrão Ferreira; Jaquelina Sonoe Ota-Arakaki; Edecio...

Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants Jeremy P. Gygi; Cole Maguire; Ravi K. Patel; Pramod Shinde; Anna Konstorum; Casey P. Shannon; Leqi Xu; Annmarie Hoch; Naresh Jayavelu; IMPACC...

Now published - details here ********** Preprint Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection Aleksandra K Drelich; Kempaiah Rayavara; Jason Hsu; Panatda Saenkham-Huntsinger...

Neutrophil extracellular traps and long COVID Shafqat, Areez; Omer, Mohamed H.; Albalkhi, Ibrahem; Alabdul Razzak, Ghazi; Abdulkader, Humzah; Abdul Rab, Saleha; Sabbah, Belal Nedal; Alkattan, Khaled; Yaqinuddin, Ahmed Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a...

Exploring microplastic impact on whole blood clotting dynamics utilizing thromboelastography Christodoulides, Alexei; Hall, Abigail; Alves, Nathan J. This study investigates the influence of microplastics on blood clotting. It addresses the lack of comprehensive research on the effects of...

Elevated cfDNA after exercise is derived primarily from mature polymorphonuclear neutrophils, with a minor contribution of cardiomyocytes Ori Fridlich; Ayelet Peretz; Ilana Fox-Fisher; Sheina Pyanzin; Ziv Dadon; Eilon Shcolnik; Ronen Sadeh; Gavriel Fialkoff; Israa Sharkia; Joshua Moss; Ludovica...

Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function Iosef, Cristiana; Knauer, Michael J.; Nicholson, Michael; Van Nynatten, Logan R.; Cepinskas, Gediminas; Draghici, Sorin; Han, Victor K. M.; Fraser, Douglas D. Aims...

Persistent serum protein signatures define an inflammatory subcategory of long COVID Talla, Aarthi; Vasaikar, Suhas V.; Szeto, Gregory Lee; Lemos, Maria P.; Czartoski, Julie L.; MacMillan, Hugh; Moodie, Zoe; Cohen, Kristen W.; Fleming, Lamar B.; Thomson, Zachary; Okada, Lauren; Becker, Lynne A...

Essentials Neutrophil extracellular trap formation (NETosis) induction levels by COVID-19 plasma correlate with illness severity, duration, platelet activation and coagulation factors. Long COVID syndrome is identified by elevated NETosis induction measurement in convalescent plasma of patients...

Abstract Although most patients recover from acute COVID-19, some experience postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of PASC is a syndrome called “long COVID-19,” reminiscent of myalgic encephalomyelitis/chronic fatigue syndrome...

Abstract Background Persistent symptoms including breathlessness, fatigue and decreased exercise tolerance have been reported in patients after acute SARS-CoV-2 infection. The biological mechanisms underlying this ‘Long COVID’ syndrome remain unknown. However, autopsy studies have highlighted...

Neutrophil Extracellular Traps (NETs) are potentially of interest to us. This image from a 2020 paper by a Chinese team (Neutrophil Extracellular Traps: Signaling Properties and Disease Relevance Tiewei Li, Zhengyan Zhang, Xiaojuan Li, Geng Dong, Min Zhang, Zhe Xu, and Junmei Yang) gives a feel...