Nirmatrelvir for acute COVID-19 to prevent long COVID (PANORAMIC Norway): a double-blind, randomised, placebo-controlled trial, 2026, Oppegaard et al.
Summary
Background
Long-term symptoms are common after acute COVID-19, particularly fatigue, cognitive problems, and dyspnoea.
Cohort studies...
Nirmatrelvir/ritonavir use reduces risk for long COVID in patients with immunodeficiency
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Selected paragraphs
Our findings highlight the potential broad benefit of nirmatrelvir/ritonavir in reducing the risk of long COVID among patients with both primary and secondary...
Efficacy Of SARS–CoV-2 Specific Antiviral Therapy for Enteroviral Myalgic Encephalomyelitis/ChronicFatigue Syndrome
John K Chia, David Wang
Background
Etiology remains elusive for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and no treatment exists. Antivirals had no efficacy...
https://www.nature.com/articles/s43856-024-00668-8
Article
Open access
Published: 06 January 2025
Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series
Alison K. Cohen,
Toni Wall Jaudon,
Eric M. Schurman,
Lisa Kava,
Julia Moore Vogel,
Julia...
Key Points
Question Is treatment with nirmatrelvir in the acute phase of SARS-CoV-2 infection associated with a lower risk of post–COVID-19 condition (PCC)?
Findings In this cohort study of 281 793 people with SARS-CoV-2 infection who had at least 1 risk factor for progression to severe...
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