nrf2

  1. hotblack

    Running a genetic stop sign accelerates oxygen metabolism and energy production in horses, 2025, Castiglione et al

    Science. (Accepted): Running a genetic stop sign accelerates oxygen metabolism and energy production in horses Castiglione, GM, Chen, X., Xu, Z., Dbouk, N.H., Bose, A., Carmona-Berrio, D., Chi, E.E., Zhou, L., Boronina, T.N., Cole, R.N., Wu, S., Liu, A., Liu, T., Lu, H., Kalbfleisch, T., Rinker...
  2. SNT Gatchaman

    Preprint Frataxin Deficiency Drives Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering Inflammatory Phenotype in Microglia,2023,Sciarretta+

    Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia Francesca Sciarretta; Fabio Zaccaria; Andrea Ninni; Veronica Ceci; Riccardo Turchi; Savina Apolloni; Valerio Chiurchiu; Marta Tiberi; Nadia D'Ambrosi; Silvia...
  3. Andy

    Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1... 2023 Galvan-Alvarez et al

    Full title: Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation Abstract When high-intensity exercise is performed until exhaustion a “functional reserve” (FR) or...
  4. cassava7

    Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of [OTC] and prescription NSAIDs, Eisenstein.., 2022

    Highlights A subset of nonsteroidal anti-inflammatory drugs (NSAIDs) activates NRF2 C151 of the chaperone protein KEAP1 is necessary for NRF2 activation by indomethacin Indomethacin reduces inflammation in endotoxemia and gout models dependent on NRF2 Summary Nonsteroidal...
  5. Andy

    Preprint: Type I interferon potentiates metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice, 2020, Lei et al

    Open access, https://www.biorxiv.org/content/10.1101/2020.09.22.308171v1.full-text
  6. Andy

    Nrf2 deficiency induces skeletal muscle mitochondrial dysfunction: a proteomics/bioinformatics approach, 2020, Willis and Deane

    In mice. Open access PDF available at https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP280758
  7. Andy

    Mechanistic Insights into the Pathophysiology of CFS/ME: Examining Nrf2 Antioxidant Gene Expression & its Role in Combating Oxidative Stress, ongoing

    Struggling at the moment to find more details about this, if/when I do I'll edit them in here. From https://cureme.lshtm.ac.uk/researchers/our-collaborative-researchers/ ETA: Added detail from the CureME collaborators page.
    • Andy
    • Thread
    • 2019 cardiology faisel khan genetics me/cfs nrf2 oxidative stress
    • Replies: 4
    • Forum: ME/CFS research
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