pet

Abstract: Background Dopaminergic neurons are vulnerable to injury from gliosis and have high density of ACE2 receptors, but the integrity of dopaminergic neurons has not been investigated in long COVID. This study examined whether vesicular monoamine transporter 2 (VMAT2) binding, index of...

Varying Levels of Inflammatory Activity in Brain and Body of Patients with Persistent Fatigue and Difficulty Concentrating After COVID-19: A TSPO PET Study A significant number of patients report persistent fatigue and difficulty concentrating after infection with severe acute respiratory...

Abstract Background: This study examined the regional distribution of glial activation in essential workers with neurological post-acute sequelae of coronavirus disease 2019 (COVID-19) infections (N-PASC). Methods: We injected ≤185 MBq of [18F]-FEPPA as an intravenous bolus and...

Persistent dysfunctions of brain metabolic connectivity in long-covid with cognitive symptoms Martini, Anna Lisa; Carli, Giulia; Caminiti, Silvia Paola; Kiferle, Lorenzo; Leo, Andrea; Perani, Daniela; Sestini, Stelvio PURPOSE Our study examines brain metabolic connectivity in SARS-CoV-2...

Frontal-striatal glucose metabolism and fatigue in patients with multiple sclerosis, long COVID, and COVID-19 recovered controls Rudroff, Thorsten This study compared brain glucose metabolism using FDG-PET in the caudate nucleus, putamen, globus pallidus, thalamus, and dorsolateral prefrontal...

Persistent brain metabolic impairment in long COVID patients with persistent clinical symptoms: a nine-month follow-up 18FFDG-PET study Horowitz, Tatiana; Dudouet, Pierre; Campion, Jacques-Yves; Kaphan, Elsa; Radulesco, Thomas; Gonzalez, Sandra; Cammilleri, Serge; Ménard, Amélie; Guedj, Eric...

Full article available: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482600

Abstract Background Brain 18F-FDG PET imaging has the potential to provide an objective assessment of brain involvement in post-COVID-19 conditions but previous studies of heterogeneous patient series yield inconsistent results. The current study aimed to investigate brain 18F-FDG PET findings...