phosphatidylcholine

I have been working on a prototype genetics app based on the hypothesis that phospholipase A2 (PLA2) activation may be increased in at least some people with ME/CFS. It is not intended to diagnose ME/CFS, and I don’t want to present it as clinically validated. It looks through a person’s...

I have started this thread to continue the discussion about possible phospholipid disruption in ME/CFS started in a different thread. @mariovitali mentioned some research papers that indicate phospholipid dysregulation- I would like to add a few other observations that may be relevant. In the...

Tamara Carnac This version is not peer-reviewed. Abstract Myalgic Encephalomyelitis (ME), sometimes known as Chronic Fatigue Syndrome (CFS), is a complex illness marked by fatigue, post-exertional malaise, cognitive dysfunction, autonomic instability, and immune abnormalities. This paper...

A Systems-Based Hypothesis for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Phosphatidylcholine Deficiency, Insulin Signaling and Noradrenergic Neuron Dysregulation Tamara Carnac pre-print Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating...

Comparative Metabolomics of Four Fatigue Disorders: Chronic Fatigue Syndrome (CFS/ME), Long COVID, Fibromyalgia (FM), and Major Depressive Disorder (MDD) Heather G Kuruvilla, Colleen Weaver, Joshua Jones, Hunter Tenpas [Poster presentation at Scholars Symposium 2024] Fatigue is a common...

Introduction: Similar to what it has been reported with preceding viral epidemics (such as MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human immunometabolism with long-term consequences. Even with underreporting, an accumulated of almost 650 million people have been...