rabgap1l

DNAm landscape up to 4 months post SARS-CoV-2 infection: insights from four population-based cohorts BACKGROUND Evidence for persistent epigenetic changes in individuals who had a mild SARS-CoV-2 infection is limited, as most DNA methylation (DNAm) studies to date have focused on either the...

RabGAP1L modulates Rab7A and Rab10 to orchestrate cell-autonomous immunity Cell-autonomous immunity protects cells by utilizing membrane trafficking to detect and counteract diverse microbial pathogens, including selective autophagy and extracellular expulsion. However, the mechanisms...

Now published, see post #5. Preprint: Abstract Fibromyalgia is a chronic heritable syndrome, with little prior genetic work taking a syndromic approach. In this study we aimed to discover genetic mechanisms underlying fibromyalgia. We conducted genome-wide association studies (GWAS) of...

Now published, see abstract in post #35. Preprint: Abstract Fibromyalgia is a common and debilitating chronic pain syndrome of poorly understood etiology. Here, we conduct a multi-ancestry genome-wide association study meta-analysis across 2,563,755 individuals (54,629 cases and 2,509,126...

From DecodeME Candidate Genes: RABGAP1L (Tier 1) • Protein: RAB GTPase-activating protein 1-like, also known as TBC1D18. UniProt. GeneCards. The allele that increases the risk of ME/CFS is associated with decreasing RABGAP1L gene expression. • Molecular function: GTP-hydrolysis activating...