small fiber neuropathy

  1. SNT Gatchaman

    Preprint Long-COVID Postural Tachycardia Syndrome: A deep phenotyping study, 2025, Larsen et al.

    Long-COVID Postural Tachycardia Syndrome: A deep phenotyping study Nicholas W Larsen; Jannika V Machnik; Jordan Seliger; Ruba Shaik; Christopher H Gibbons; Paul J Utz; Maarten G Lansberg; Srikanth Muppidi; Safwan Jaradeh; Mitchell G Miglis BACKGROUND Postural tachycardia syndrome (POTS) has...
    • SNT Gatchaman
    • Thread
    • amyloid doppler ultrasound hypocapnia nirs orthostatic intolerance pots sfn small fiber neuropathy synucleinopathy tilt table test
    • Replies: 17
    • Forum: Long Covid research
  2. SNT Gatchaman

    Preprint Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies, 2025, Maguire et al.

    Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies Cole Maguire; Kristina Kashyap; Elizabeth Williams; Aziz Rija; Maisey Schuler; Cheyenne Ahamed; Chumeng Wang; Aurelia Mena; Jeffrey Saniuk; Johanna Busch; Sara Austin; Mary Kelley...
    • SNT Gatchaman
    • Thread
    • autoimmunity gangliosides immunoglobulin ivig neuropathy sfn skin biopsy small fiber neuropathy
    • Replies: 6
    • Forum: Long Covid research
  3. V

    Efficacy of rituximab on antibody-positive small fiber neuropathy: A series of 5 cases, Chan, et al, 2025

    research from Singapore… @Jonathan Edwards? paywall for me. https://www.jni-journal.com/article/S0165-5728(25)00039-6/abstract Efficacy of rituximab on antibody-positive small fiber neuropathy: A series of 5 cases Results Two patients were positive for anti-TS-HDS, one for anti-plexin D1...
  4. forestglip

    Review Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review, 2025, Bandinelli et al

    Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review Francesca Bandinelli, Marco Di Carlo, Virginia Alba Colantuono, Filippo Nozzoli, Fausto Salaffi, Barbara Chiocchetti, Elena Nucci, Alessandra Mastricci, Eleonora Gherardi, Mirko...
  5. Hoopoe

    Can small fiber neuropathy present like ME/CFS?

    I was diagnosed with small fiber neuropathy via skin biopsy. I'm trying to understand my health issues and I'm wondering if it's possible to have a painless form of SFN that presents with fatigue, poor sleep, exertion intolerance, mild intolerance of upright position. I later developed more...
  6. SNT Gatchaman

    Small fiber neuropathy in the post-COVID condition and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome…, 2025, Azcue+

    Small fiber neuropathy in the post-COVID condition and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical significance and diagnostic challenges Naiara Azcue; Sara Teijeira-Portas; Beatriz Tijero-Merino; Marian Acera; Tamara Fernández-Valle; Unai Ayala; Maitane Barrenechea; Ane...
  7. SNT Gatchaman

    Association Between NK Cell Genetic Variants and the Development of Long COVID Associated- and Prepandemic Small Fiber Neuropathy, 2024, Graninger+

    Association Between NK Cell Genetic Variants and the Development of Long COVID Associated- and Prepandemic Small Fiber Neuropathy Marianne Graninger; Verena Endmayr; Laura M. Kühner; Sarah M. Berger; Paulus Rommer; Sigrid Klotz; Ellen Gelpi; Hannes Vietzen; Romana Höftberger; Elisabeth...
  8. Hoopoe

    Preprint Beyond pain: Using Unsupervised Machine Learning to Identify Phenotypic Clusters of Small Fiber Neuropathy 2024 Murin et al

    I found this interesting because it claims that in small fiber neuropathy, most patients had intense fatigue, myalgia, and subjective weakness and lower intensity of neuropathic pain. https://www.medrxiv.org/content/10.1101/2024.09.09.24313341v1.full.pdf
  9. SNT Gatchaman

    Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy, 2024, Oaklander et al.

    Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy Anne Louise Oaklander, Julia Allen, Nadja Dietliker, Einar P. Wilder-Smith OBJECTIVES To expand understanding of the pathogenesis, presentations, and treatment of initially idiopathic small fiber polyneuropathy (SFN). METHODS...
  10. SNT Gatchaman

    Broadening the Genetic Spectrum of Painful Small-Fiber Neuropathy through Whole-Exome Study in Early-Onset Cases, 2024, Misra et al.

    Broadening the Genetic Spectrum of Painful Small-Fiber Neuropathy through Whole-Exome Study in Early-Onset Cases Misra, Kaalindi; Ślęczkowska, Milena; Santoro, Silvia; Gerrits, Monique M.; Mascia, Elisabetta; Marchi, Margherita; Salvi, Erika; Smeets, Hubert J. M.; Hoeijmakers, Janneke G. J...
  11. Hoopoe

    SCN9A variant and dysautonomia

    A clinical geneticist believes that a rare variant in the SCN9A gene could be responsible for at least a part of my symptoms. The variant is extremely rare (1 in 1.4 million alleles) and not found in healthy people. The gene is associated with small fibre neuropathy which would fit, but there...
  12. Andy

    Validation of symptom measures in patients under investigation for postural orthostatic tachycardia syndrome (POTS):... 2023 Iris Knoop, Moss-Morris

    Full title: Validation of symptom measures in patients under investigation for postural orthostatic tachycardia syndrome (POTS): The Orthostatic Grading Scale (OGS) and the Symptom Screen for Small-fiber Polyneuropathy (SSS) Highlights More standardized symptom reporting is needed in Postural...
  13. V

    Winsantor Phase 2 small fiber neuropathy drug (WST-057) trial news.

    I recieved this newsletter and could not find it posted on the Internet, so I thought I’d post the text. This is a newsletter from a small company, Winsantor, who is testing a topical drug (WST-057) to see if it increases small fiber nerve density (and improve symptoms?) in diabetic patients...
  14. ahimsa

    Medscape: 3 Years Into Long COVID: Where Do We Go From Here? (by Lisa McCorkell, Patient-Led Research Collaborative)

    3 Years Into Long COVID: Where Do We Go From Here? https://www.medscape.com/viewarticle/993827 "... approximately 6% of all US adults are currently experiencing long COVID, with Hispanic/Latinx individuals, transgender individuals, and cis female individuals facing the highest rates."...
    • ahimsa
    • Thread
    • cognitive dysfunction covid long covid mast cell activation syndrome mecfs medscape post exertional malaise postural orthostathic tachycardia syndrome pots prevalence reinfection small fiber neuropathy
    • Replies: 6
    • Forum: Long Covid news
  15. Sly Saint

    Hypothesis [ME/CFS] and Comorbidities: Linked by Vascular Pathomechanisms and Vasoactive Mediators? 2023, Wirth and Löhn

    Wirth and Lohn Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is often associated with various other syndromes or conditions including mast cell activation (MCA), dysmenorrhea and endometriosis, postural tachycardia (POTS) and small fiber neuropathy (SFN). The causes of...
    • Sly Saint
    • Thread
    • endometriosis mcas me/cfs pots small fiber neuropathy vascular
    • Replies: 7
    • Forum: ME/CFS research
  16. V

    ME/CFS Pathophysiology Investigated by Invasive Cardiopulmonary Exercise Testing and Autonomic Function Testing, 2023, Squires, ..Systrom et. al.

    ME/CFS Pathophysiology Investigated by Invasive Cardiopulmonary Exercise Testing and Autonomic Function Testing. J. Squires 2, K. Wichmann Madsen 2, M.C. Stovall 2, S. Al-Zayer 2, W. Xiao 3, C.-J. Chang 3, P. Novak 1, D.M. Systrom 2...
    • voner
    • Thread
    • cardiovascular me/cfs pots small fiber neuropathy systrom
    • Replies: 5
    • Forum: ME/CFS research
  17. SNT Gatchaman

    Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy, 2022, Andelic et al.

    Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy Andelic, Mirna; Salvi, Erika; Marcuzzo, Stefania; Marchi, Margherita; Lombardi, Raffaella; Cartelli, Daniele; Cazzato, Daniele; Mehmeti, Elkadia; Gelemanovic, Andrea; Paolini, Matilde; Pardo...
  18. V

    Cytokine expression profiles in white blood cells of patients with small fiber neuropathy, Kreß, L., et al. 2023

    Abstract Background The role of cytokines in the pathophysiology, diagnosis, and prognosis of small fiber neuropathy (SFN) is incompletely understood. We studied expression profiles of selected pro- and anti-inflammatory cytokines in RNA from white blood cells (WBC) of patients with a medical...
  19. Hutan

    Peripheral Nerve Society - grants for research

    2022 https://www.pnsociety.com/i4a/pages/index.cfm?pageid=3313 AFM & GBS GRANTS The NIAID, NINDS, and NICHD have jointly issued a Notice of Special Interest encouraging new applications and request for supplements to existing grants (competitive revisions or administrative supplements) to...
    • Hutan
    • Thread
    • funding peripheral neuropathy research small fiber neuropathy
    • Replies: 2
    • Forum: ME/CFS research news
  20. Andy

    Preprint: Neuropathic symptoms with SARS-CoV-2 vaccination, 2022, Safavi, Walitt, Oaklander, Nath et al

    Abstract Background and Objectives Various peripheral neuropathies, particularly those with sensory and autonomic dysfunction may occur during or shortly after acute COVID-19 illnesses. These appear most likely to reflect immune dysregulation. If similar manifestations can occur with the...
    • Andy
    • Thread
    • autonomic dysfunction avindra nath brian walitt neurological nih small fiber neuropathy symptoms vaccination
    • Replies: 3
    • Forum: Long Covid research
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